Cat: IPD-X38663

Recombinant Mouse SYN2 Protein,His

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关键信息

  • 基因名

    SYN2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SYNII; SYNIIa; SYNIIb

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q64332

  • 表达区间

    Leu88~Thr422

  • 分子量

    41kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

The SYN2 (Synaptotagmin 2) recombinant protein has garnered significant interest in neuroscientific research, particularly in the context of synaptic transmission and neurodevelopmental disorders. SYN2 is a member of the synaptotagmin family, proteins that play a crucial role in neurotransmitter release by acting as calcium sensors in synaptic vesicles. Alterations in SYN2 expression or function have been associated with various neurological conditions, including autism spectrum disorders and schizophrenia. Understanding the molecular mechanisms underlying SYN2 activity and its interactions with other synaptic proteins is crucial for elucidating the complexities of synaptic regulation. Recent advances in recombinant DNA technology have enabled the production and study of SYN2 in various model systems, allowing researchers to investigate its structure, function, and involvement in synaptic plasticity. The study of SYN2 as a recombinant protein aims not only to clarify its role in synaptic dynamics but also to identify potential therapeutic targets for treating synaptic dysfunctions associated with neurodevelopmental and psychiatric disorders.

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