关键信息
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基因名
CENTa1
- 应用
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别名
CENT-A1; ADAP1; GCS1L; P42IP4; Arf-GAP with dual PH domain-containing protein 1; Putative MAPK-activating protein PM25
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75689
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表达区间
Ser45~Asp356
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分子量
42kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CENTa1, a noteworthy protein implicated in various cellular processes, has garnered increasing attention in the field of molecular biology and biochemistry. Initially identified in studies exploring protein interactions within the centrosome, CENTa1 plays a crucial role in cellular architecture and mitotic regulation. Over the years, research has revealed its involvement in neural development and function, indicating potential links to neurodevelopmental disorders. The protein's multifaceted roles suggest it may act as a critical mediator between centrosomal function and various signaling pathways. With advances in recombinant DNA technology, scientists have successfully produced CENTa1 as a recombinant protein, allowing for detailed in vitro studies regarding its structural properties and functional significance. The development of purified CENTa1 has enabled researchers to investigate its interactions with other proteins, further elucidating its role in cellular dynamics and disease mechanisms. Understanding CENTa1's molecular functions could provide insights into its involvement in cancer, as aberrations in centrosomal proteins are frequently observed in malignancies. Ongoing studies seek to uncover potential therapeutic targets associated with CENTa1, aiming to translate basic research findings into clinical applications. In essence, the investigation of CENTa1 as a recombinant protein represents a promising frontier in understanding fundamental biological processes and developing novel strategies for treating related diseases.
