WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 | Human,Mouse,Rat |
ICC | 1/50-1/200 | Human,Mouse,Rat |
FCM | 1/20-1/100 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | SA 2; SA-2; SA2; SCC3 homolog 2; SCC3B; stag2; Stromal antigen 2;;Cohesin subunit SA 2 |
WB Predicted band size | 141 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human Cohesin subunit SA 2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于SA2抗体的3篇参考文献示例(注:文献为示例性内容,实际引用时请核实真实来源):
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1. **文献名称**: "STAG2 mutations alter cohesion proteins and chromosome segregation in bladder cancer"
**作者**: Solomon DA, et al.
**摘要**: 该研究利用特异性SA2抗体探究了STAG2基因突变在膀胱癌中的作用,发现突变导致粘连蛋白复合体功能异常,引发染色体不稳定性,促进肿瘤发展。
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2. **文献名称**: "Cohesin-SA2 deficiency drives aneuploidy and tumorigenesis in mice"
**作者**: Remeseiro S, et al.
**摘要**: 通过SA2抗体在小鼠模型中检测Cohesin复合体,发现SA2缺失导致染色体分离错误和基因组不稳定,揭示了其在抑制肿瘤发生中的关键作用。
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3. **文献名称**: "Antibody-based profiling of STAG2 expression in human cancers"
**作者**: Kim JS, et al.
**摘要**: 本研究开发了一种高特异性SA2单克隆抗体,用于检测多种癌症组织中STAG2蛋白的表达水平,发现其低表达与预后不良和化疗耐药性相关。
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(注:以上文献信息为虚拟示例,实际引用请通过学术数据库获取真实文献。)
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