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产品描述：人胰岛素样生长因子2受体(IGF-2R)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的IGF2R含量。IGF2R是一种重要靶点。其在细胞内参与胰岛素样生长因子2的代谢与调控，与细胞生长、增殖等过程相关。研究关注其在肿瘤发生发展中的机制，探索其作为肿瘤诊断标志物及治疗靶点的潜力，为开发相关药物和疗法提供依据。试剂盒检测范围为312.5 pg/mL-20000 pg/mL，特别适用于基础科研领域如肿瘤微环境研究、代谢调控机制探索、细胞信号通路分析等方向本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：300 kDa mannose 6 phosphate receptor ELISA Kit; 300 kDa mannose 6-phosphate receptor ELISA Kit; Cation independent mannose 6 phosphate receptor ELISA Kit; Cation-independent mannose-6-phosphate receptor ELISA Kit; CD222 ELISA Kit; CD222 antigen ELISA Kit; CI Man 6 P receptor ELISA Kit; CI Man-6-P receptor ELISA Kit; CI MPR ELISA Kit; CI-M6PR ELISA Kit; CI-MPR ELISA Kit; CIMPR ELISA Kit; IGF 2 receptor ELISA Kit; IGF 2R ELISA Kit; IGF II receptor ELISA Kit; IGF-II receptor ELISA Kit; IGF2 receptor ELISA Kit; Igf2r ELISA Kit; Insulin like growth factor 2 receptor ELISA Kit; Insulin like growth factor II receptor ELISA Kit; Insulin-like growth factor 2 receptor ELISA Kit; Insulin-like growth factor II receptor ELISA Kit; M6P R ELISA Kit; M6P/IGF2 receptor ELISA Kit; M6P/IGF2R ELISA Kit; M6PR ELISA Kit; mannose 6 phosphate receptor ELISA Kit; mannose 6 phosphate receptor, cation independent ELISA Kit; MPR 300 ELISA Kit; MPR300 ELISA Kit; MPRI ELISA Kit; MPRI_HUMAN ELISA Kit
缩写：IGF2R
Uniprot No.：P11717
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates
检测范围：312.5 pg/mL-20000 pg/mL
灵敏度：78.1 pg/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Signal Transduction
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<8% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<10% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human IGF-2R in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 97 | ||||
| Range % | 92-103 | |||||
| 1:2 | Average % | 90 | ||||
| Range % | 83-96 | |||||
| 1:4 | Average % | 102 | ||||
| Range % | 99-105 | |||||
| 1:8 | Average % | 86 | ||||
| Range % | 81-92 | |||||
回收率：
| The recovery of human IGF-2R spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 92 | 87-98 | ||||
| EDTA plasma (n=4) | 89 | 82-95 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| pg/mlOD1OD2AverageCorrected200002.8212.7522.7872.666100002.4202.2792.3502.22950001.7641.7891.7771.65625000.9411.0020.9720.85112500.5270.5550.5410.4206250.3180.3460.3320.211312.50.2140.2250.2200.09900.1260.1160.121 | ||||||
货期：3-5 working days
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