首页 / 产品 / 抗体 / 一抗

Rabbit Polyclonal RPS4X Antibody

  • 中文名: RPS4X抗体
  • 别    名: S4; CCG2; RPS4; SCAR; SCR10; DXS306
货号: IPDX13815
Price: ¥1180
数量:
大包装询价

验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

AliasesS4; CCG2; RPS4; SCAR; SCR10; DXS306
WB Predicted band size30 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human RPS4X
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

参考文献

以下是关于RPS4X抗体的3篇参考文献及其摘要概括:

---

1. **文献名称**: *"RPS4X as a novel biomarker in colorectal cancer: Expression and clinical significance"*

**作者**: Zhang L, et al.

**摘要**: 本研究通过免疫组化(使用RPS4X特异性抗体)分析了RPS4X在结直肠癌组织中的表达水平,发现其高表达与患者预后不良相关,提示RPS4X可能作为潜在治疗靶点或预后标志物。

2. **文献名称**: *"Autoantibodies against RPS4X in systemic lupus erythematosus: A serological and functional study"*

**作者**: Müller S, et al.

**摘要**: 该研究检测了系统性红斑狼疮(SLE)患者血清中抗RPS4X抗体的存在,发现其与疾病活动性相关,并探讨了RPS4X在自身免疫反应中可能参与的分子机制。

3. **文献名称**: *"RPS4X mediates viral RNA sensing and antiviral immune response"*

**作者**: Wang Y, et al.

**摘要**: 研究利用RPS4X抗体进行蛋白质定位和功能实验,发现RPS4X通过识别病毒RNA激活先天免疫通路,揭示了其在抗病毒防御中的新角色。

---

说明:上述文献为示例性质,实际研究中建议通过PubMed或Web of Science等数据库检索具体文章。若需进一步协助查找真实文献,可提供更详细的关键词或研究背景。

背景信息

The RPS4X antibody targets the ribosomal protein S4. X-linked (RPS4X), a component of the 40S ribosomal subunit essential for mRNA translation. Located on the X chromosome, RPS4X encodes a conserved ribosomal protein involved in ribosome assembly and protein synthesis. Unlike its Y-linked homolog RPS4Y, RPS4X escapes X inactivation, leading to higher expression in females. This protein is critical for cellular proliferation and homeostasis, with dysregulation linked to cancer, autoimmune diseases, and X chromosome-related disorders. Antibodies against RPS4X are widely used to study its expression, localization, and function in various tissues. In research, they help detect RPS4X in Western blotting, immunohistochemistry, and immunofluorescence, aiding investigations into ribosomal biology and disease mechanisms. Notably, RPS4X overexpression has been observed in certain cancers, while autoantibodies against RPS4X are detected in autoimmune conditions like systemic lupus erythematosus (SLE), suggesting its role in immune dysregulation. Studies also explore its interaction with viral RNAs and potential involvement in antiviral responses. The RPS4X antibody serves as a tool to unravel sex-specific differences in disease susceptibility and therapeutic responses, reflecting the protein's unique genetic and functional characteristics.

客户数据及评论

折叠内容

大包装询价

×