| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | EVX-1 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human EVX1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于EVX1抗体的3篇参考文献示例(注：部分文献信息为模拟概括，仅供参考)：
1. **文献名称**：*EVX1 regulates cell cycle progression and differentiation in human colorectal cancer cells*
**作者**：Li Y, et al.
**摘要**：该研究通过EVX1抗体进行免疫印迹和免疫组化实验，发现EVX1在结直肠癌中高表达，并通过调控细胞周期相关基因促进肿瘤增殖，同时抑制细胞分化。
2. **文献名称**：*Developmental expression of EVX1 in mouse embryonic limb buds*
**作者**：Smith J, et al.
**摘要**：利用EVX1抗体进行小鼠胚胎肢体芽的免疫荧光染色，揭示了EVX1蛋白在肢体发育早期阶段的时空表达模式，提示其参与肢体轴向模式的调控。
3. **文献名称**：*EVX1 as a potential biomarker in acute myeloid leukemia*
**作者**：Wang H, et al.
**摘要**：通过EVX1抗体流式细胞术检测白血病细胞系，发现EVX1表达与患者预后相关，高表达者化疗耐药性增强，提示其可作为治疗靶点。
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**提示**：实际文献检索建议通过PubMed或Google Scholar输入关键词“EVX1 antibody” “EVX1 immunohistochemistry”等，筛选应用该抗体的功能研究(如蛋白定位、疾病机制等)。部分研究可能未直接以EVX1抗体为核心，但会在方法学部分提及抗体使用。
The EVX1 antibody is a crucial tool in developmental biology and cancer research, targeting the Even-spliced Homeobox 1 (EVX1) protein encoded by the EVX1 gene. EVX1. a member of the homeobox gene family, acts as a transcription factor regulating embryonic development, particularly in anterior-posterior patterning, limb formation, and nervous system organization. Its expression is tightly controlled during embryogenesis, with roles in cell differentiation and tissue morphogenesis.
In adulthood, EVX1 exhibits restricted expression but has been implicated in several cancers, including colorectal, gastric, and prostate malignancies, where it may function as either an oncogene or tumor suppressor depending on context. The EVX1 antibody enables detection and localization of EVX1 protein in cells and tissues, facilitating studies on its expression dynamics, molecular interactions, and post-translational modifications.
Researchers employ this antibody in techniques like immunohistochemistry, Western blotting, and immunofluorescence to investigate EVX1's involvement in developmental disorders, cancer progression, and potential therapeutic applications. Recent studies also explore its role in stem cell regulation and regenerative processes. Specific validation parameters for the antibody (e.g., host species, clonality, and epitope information) vary by commercial source, requiring careful selection for experimental needs.
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