关键信息
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基因名
Semenogelin-1
- 应用
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别名
Cancer/testis antigen 103 Semenogelin I Short name: SGI Cleaved into the following 3 chains: Alpha-inhibin-92 Alpha-inhibin-31 Seminal basic protein
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04279
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表达区间
24-402aa
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分子量
58.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Semenogelin-1 (SEMG1) is a significant protein component found in human semen, primarily involved in sperm function and fertility. As a major gel-forming protein in seminal plasma, SEMG1 plays a crucial role in the formation of the semen coagulum, which helps to stabilize sperm within the female reproductive tract, ultimately facilitating successful fertilization. Recent research has highlighted the significance of SEMG1 in regulating sperm motility and the subsequent release of sperm post-ejaculation. Its structure comprises multiple domains that contribute to its gel-forming properties and interaction with various seminal proteins. Furthermore, alterations in SEMG1 expression or functioning have been associated with male infertility, making it a potential biomarker for reproductive health assessments. As a result, the recombinant production of SEMG1 has garnered interest in both basic research and clinical applications. Researchers are exploring the potential of SEMG1 as a therapeutic target or a diagnostic tool to better understand male reproductive issues. Investigations into its molecular mechanisms, interactions with other proteins, and overall role in sperm biology are ongoing, highlighting its importance in reproductive medicine and fertility treatments. Understanding SEMG1's functions could pave the way for innovative strategies to enhance male fertility and address infertility disorders globally. Overall, SEMG1 presents a promising avenue for research in reproductive biology, providing insights that may lead to improved fertility treatments and a deeper comprehension of sperm dynamics.
