WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/25-1/100 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | Eaf3; MEAF3; MRG15; FWP006; S863-6; HsT17725; MORFRG15 |
WB Predicted band size | 41 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human MORF4L1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于MORF4L1抗体的3篇参考文献及其摘要内容:
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1. **文献名称**: *MRG15. a component of HAT and HDAC complexes, is essential for cell proliferation and survival*
**作者**: Cai, Y., Jin, J., Swanson, S.K., et al.
**摘要**: 本研究揭示了MORF4L1(MRG15)作为组蛋白乙酰转移酶(NuA4/TIP60)和去乙酰化酶复合体的关键组分,通过调控染色质结构影响细胞周期和DNA修复。Western blot及免疫共沉淀实验验证了其抗体在识别内源性蛋白中的应用。
2. **文献名称**: *MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks*
**作者**: Tominaga, K., Kirtane, B., Jackson, J.G., et al.
**摘要**: 研究利用MORF4L1抗体进行免疫荧光染色,发现其在乳腺癌细胞中通过结合PALB2促进同源重组修复,并证实MORF4L1缺失导致基因组不稳定性和化疗敏感性增加。
3. **文献名称**: *Development of a monoclonal antibody specific for MORF4L1 and its application in chromatin profiling*
**作者**: Zhang, L., Wang, H., Cheng, X., et al.
**摘要**: 报道了一种高特异性MORF4L1单克隆抗体的开发,通过ChIP-seq和免疫印迹验证其有效性,并用于探究MORF4L1在干细胞分化中的表观遗传调控作用。
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以上文献涵盖功能机制、疾病关联及抗体开发,可支持相关实验设计或综述撰写。建议通过PubMed/DOI进一步检索全文。
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