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Rabbit Polyclonal RPL35 Antibody

  • 中文名: RPL35抗体
  • 别    名: L35
货号: IPDX10234
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/50-1/200 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

参考文献

以下是关于RPL35抗体的模拟参考文献示例(仅供参考,实际文献需通过学术数据库检索):

1. **"RPL35 as a novel biomarker in hepatocellular carcinoma: Expression analysis and clinical significance"**

- 作者:Li X, et al.

- 摘要:研究通过免疫组化(使用RPL35特异性抗体)检测肝细胞癌组织中RPL35的表达水平,发现其高表达与患者预后不良相关,提示RPL35可能作为肝癌治疗的潜在靶点。

2. **"Role of RPL35 in regulating cell cycle progression via p53 signaling pathway"**

- 作者:Wang Y, et al.

- 摘要:利用RPL35抗体进行Western blot和免疫荧光实验,证明RPL35通过调控p53通路影响细胞周期停滞,敲低RPL35导致癌细胞增殖抑制。

3. **"Development and validation of a high-specificity monoclonal antibody for human RPL35"**

- 作者:Zhang H, et al.

- 摘要:报道了一种新型RPL35单克隆抗体的制备与验证,通过ELISA、免疫印迹和免疫沉淀实验证实其高特异性和灵敏度,为后续研究提供工具。

4. **"RPL35 modulates ribosome biogenesis and promotes colorectal cancer metastasis"**

- 作者:Chen J, et al.

- 摘要:研究通过RPL35抗体检测发现,RPL35在结直肠癌转移灶中表达显著升高,机制上通过促进核糖体生物合成驱动肿瘤侵袭转移。

(注:以上为模拟生成的参考文献,实际引用请以真实文献为准。)

背景信息

The RPL35 antibody is a crucial tool for studying ribosomal protein L35 (RPL35), a component of the 60S large ribosomal subunit involved in protein synthesis. RPL35. encoded by the RPL35 gene, plays a role in ribosome assembly and translational fidelity. Dysregulation of RPL35 has been linked to various diseases, including cancers (e.g., hepatocellular carcinoma, colorectal cancer) and ribosomopathies, highlighting its importance in cellular homeostasis. The antibody specifically detects RPL35 in applications like Western blotting, immunohistochemistry, and immunofluorescence, enabling researchers to analyze its expression, localization, and interactions. Its utility extends to investigating ribosomal stress responses, cancer progression mechanisms, and potential therapeutic targets. Commercially available RPL35 antibodies are typically produced in hosts like rabbits or mice, targeting specific epitopes with validated specificity. Recent studies also explore its role in viral infections, where ribosomal proteins may influence pathogen replication. By facilitating precise detection, the RPL35 antibody supports advancements in understanding ribosome biology and disease pathology, bridging basic research and clinical applications.

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