| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | JM11 |
| WB Predicted band size | 68 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human CCDC120 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CCDC120抗体的3篇模拟参考文献(示例仅供格式参考，实际文献需通过学术数据库查询)：
1. **文献名称**: *CCDC120 Antibody Development and Its Role in Cell Cycle Regulation*
**作者**: Li, X. et al.
**摘要**: 该研究开发了一种特异性识别CCDC120蛋白的多克隆抗体，并通过免疫印迹和免疫荧光验证其在细胞周期调控中的作用，发现CCDC120在有丝分裂中可能与纺锤体组装相关。
2. **文献名称**: *CCDC120 Expression in Breast Cancer: A Novel Prognostic Marker*
**作者**: Wang, Y. et al.
**摘要**: 利用CCDC120抗体对乳腺癌组织进行免疫组化分析，发现高表达CCDC120与患者生存率降低相关，提示其可能作为潜在治疗靶点。
3. **文献名称**: *Characterization of CCDC120 Interaction with Autophagy Proteins Using Monoclonal Antibodies*
**作者**: Zhang, R. et al.
**摘要**: 研究通过制备抗CCDC120的单克隆抗体，揭示了其与自噬相关蛋白LC3的相互作用，为探究CCDC120在代谢疾病中的功能提供了工具。
**提示**：以上为模拟示例，实际文献建议通过PubMed、Google Scholar等平台以“CCDC120 antibody”或“CCDC120 function”为关键词检索。
The CCDC120 antibody targets the Coiled-Coil Domain Containing 120 (CCDC120) protein, a less characterized member of the coiled-coil domain-containing protein family. These proteins typically participate in cellular processes like cytoskeletal organization, intracellular transport, and cell division through their coiled-coil domains. CCDC120 is speculated to play roles in cellular structural maintenance or signaling, though its exact biological functions remain under investigation. Studies suggest potential links to cancer progression, as aberrant expression of CCDC120 has been observed in certain tumors, implicating it in cell proliferation or metastasis.
The CCDC120 antibody is primarily used in research to detect and quantify CCDC120 expression in tissues or cell lines via techniques like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF). It aids in elucidating the protein's localization, expression patterns, and interactions with other molecules. Commercial antibodies are often raised in rabbits or mice, validated for specificity using knockout controls or siRNA-mediated knockdown.
Current research focuses on clarifying CCDC120's role in disease mechanisms, particularly cancer, and its potential as a diagnostic or prognostic biomarker. Further studies are needed to unravel its molecular pathways and therapeutic relevance. The antibody remains a critical tool for advancing understanding of CCDC120's contributions to cellular physiology and pathology.
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