关键信息
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基因名
CD9
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简介
CD9 protein is an integral membrane protein that plays a critical regulatory role in processes such as sperm-egg fusion, platelet activation, and cell adhesion. CD9 is critical for sperm-egg fusion, coordinating multi-protein complexes on the oocyte surface. CD9 Protein, Human (HEK293, His) is the recombinant human-derived CD9 protein, expressed by HEK293 , with C-6*His labeled tag.
- 应用
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别名
CD9 antigen; MIC3; TSPAN29; DRAP-27; MRP1; BTCC1; CD9
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P21926
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表达区间
S112-I195
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蛋白长度
Extracellular Domain
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分子量
10 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CD9 is a tetraspanin protein that plays a crucial role in various cellular processes, including cell adhesion, activation, and signaling. It is expressed in numerous cell types, particularly in immune cells and platelets, where it is involved in modulating interactions with other cells and the extracellular matrix. Research on CD9 has gained momentum due to its implications in cancer biology, where it has been associated with tumor progression, metastasis, and immune evasion. In recent years, studies have highlighted the potential of CD9 as a biomarker for diagnosing certain types of cancers and as a target for therapeutic interventions. Recombination technology has enabled the production of recombinant CD9 proteins, facilitating detailed investigations into their structure and function. These recombinant proteins are valuable for elucidating the molecular mechanisms by which CD9 influences cellular behavior and for developing CD9-targeted therapies. As the understanding of CD9's roles in both normal physiology and disease progresses, it is becoming increasingly recognized as a promising avenue for clinical research, particularly in oncology and immunotherapy.
