关键信息
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基因名
CD84/SLAMF5
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简介
CD84/SLAMF5 is an autoligand receptor of the SLAM family that regulates immune cell activation and differentiation through homotypic or heterotypic interactions. Its activity is affected by SH2D1A/SAP and SH2D1B/EAT-2. CD84/SLAMF5 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-10*His labeled tag.
- 应用
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别名
CD84; SLAM family member 5; SLAMF5
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种属
Mouse
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表达系统
HEK293
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标签
C-10*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q18PI6-1
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表达区间
K22-V221
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氨基酸序列
KDADPMVMNGILGESVTFLLNIQEPKKIDNIAWTSQSSVAFIKPGVNKAEVTITQGTYKGRIEIIDQKYDLVIRDLRMEDAGTYKADINEENEETITKIYYLHIYRRLKTPKITQSLISSLNNTCNITLTCSVEKEEKDVTYSWSPFGEKSNVLQIVHSPMDQKLTYTCTAQNPVSNSSDSVTVQQPCTDTPSFHPRHAV
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蛋白长度
Extracellular Domain
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分子量
37-42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Recombinant Human OSMR (Oncostatin M Receptor, OSMRβ) is a type I transmembrane receptor and an essential component of the oncostatin M (OSM) signaling pathway. OSMR forms a functional receptor complex with GP130 (IL6ST) to recognize the IL-6 family cytokine OSM. Upon ligand binding, the OSMR/GP130 complex triggers downstream signaling such as JAK/STAT, MAPK, and PI3K/AKT pathways, regulating inflammation, cell growth, differentiation, tissue remodeling, and fibrosis.
OSMR is expressed in multiple cell types including epithelial cells, fibroblasts, and endothelial cells, and aberrant OSM–OSMR signaling has been linked to chronic inflammatory diseases, fibrosis, and cancer progression. Recombinant Human OSMR Protein is widely used for ligand–receptor binding studies, antibody screening and characterization, and assay development in therapeutic research targeting OSM-driven biology.
