关键信息
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基因名
TLR2
- 应用
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别名
CD282; TIL4; Toll/interleukin-1 receptor-like protein 4
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by reducing SDS-PAGE.
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蛋白编号
O60603
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表达区间
Glu21~Thr588
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分子量
66kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Toll-like receptor 2 (TLR2) is a crucial component of the innate immune system, recognizing various pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and fungi. Research into TLR2 has gained significant attention due to its role in modulating immune responses and its involvement in various infectious and inflammatory diseases. TLR2 recognizes ligands such as lipoproteins and peptidoglycans, initiating signaling pathways that lead to the production of pro-inflammatory cytokines and the activation of immune cells. The study of recombinant TLR2 proteins has enabled scientists to investigate the receptor's structure-function relationship, ligand-binding interactions, and downstream signaling mechanisms. Recombinant TLR2 proteins serve as valuable tools in understanding the receptor's role in immunological responses, potential therapeutic applications, and vaccine development. Furthermore, characterizing TLR2 through recombinant technology facilitates the exploration of its involvement in autoimmune diseases, chronic inflammation, and cancer, making it a promising target for novel immunotherapeutic strategies. Overall, research on TLR2 recombinant proteins is essential for unveiling new insights into immune regulation and developing strategies for disease intervention.
