关键信息
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基因名
CD157
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简介
CD157 protein catalyzes the synthesis of cADPR from NAD(+) and hydrolyzes cADPR to ADPR. cADPR acts as a second messenger, releasing calcium from intracellular stores. CD157 protein may also contribute to pre-B cell growth. CD157 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD157 protein, expressed by HEK293 , with C-hFc labeled tag.
- 应用
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别名
ADP-ribosyl cyclase; BST1; Cyclic ADP-ribose hydrolase 2; CD157
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种属
Rat
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表达系统
HEK293
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标签
C-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q63072
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表达区间
R34-E293
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蛋白长度
Partial
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分子量
67 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CD157, also known as bone marrow stromal antigen 1 (BSA-1), is a member of the NAD+-glycohydrolase family and is primarily expressed on the surface of various immune cells, including monocytes and lymphocytes. It plays a significant role in modulating immune responses, promoting cell adhesion, and influencing cellular signaling pathways. The interest in CD157 has surged in recent years due to its involvement in immune regulation and potential implications in various diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. Recombinant CD157 protein has emerged as a valuable tool for researchers to study its functional roles and interactions within the immune system. By creating a purified form of this protein, scientists can perform in-depth analyses of its enzymatic activities, receptor interactions, and potential therapeutic applications. This research aims to elucidate the intricate mechanisms by which CD157 modulates immune responses and to explore its potential as a target for novel immunotherapies. Understanding the structure and function of CD157 can lead to innovative strategies for manipulative interventions in diseases exacerbated by immune dysregulation, thereby highlighting its importance in the field of immunology and therapeutic development.
