关键信息
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基因名
TLX2
- 应用
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别名
TLX2; HOX11L1; NCX; T-cell leukemia homeobox Protein 2; Homeobox Protein Hox-11L1; Neural crest homeobox Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43763
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表达区间
1-284 aa
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氨基酸序列
MEPGMLGPHN LPHHEPISFG IDQILSGPET PGGGLGLGRG GQGHGENGAF SGGYHGASGY GPAGSLAPLP GSSGVGPGGV IRVPAHRPLP VPPPAGGAPA VPGPSGLGGA GGLAGLTFPW MDSGRRFAKD RLTAALSPFS GTRRIGHPYQ NRTPPKRKKP RTSFSRSQVL ELERRFLRQK YLASAERAAL AKALRMTDAQ VKTWFQNRRT KWRRQTAEER EAERHRAGRL LLHLQQDALP RPLRPPLPPD PLCLHNSSLF ALQNLQPWAE DNKVASVSGL ASVV
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分子量
30.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
TLX2, a member of the T-cell leukemia homeobox (TLX) gene family, plays a critical role in various biological processes, including embryonic development and cell fate determination. Its dysregulation has been implicated in several cancers, particularly in hematological malignancies. Research has shown that TLX2 is involved in the regulation of stem cell properties and differentiation, making it a potential target for therapeutic interventions. The recombinant TLX2 protein has emerged as a valuable tool in understanding the molecular mechanisms underlying its functions. By studying the structure and activity of the TLX2 protein, researchers aim to unravel its interactions with target genes and pathways that contribute to oncogenesis. Additionally, recombinant TLX2 can be utilized to explore its role in normal cellular processes and the signaling networks that govern stem cell behavior. As a result, TLX2 not only serves as a biomarker for certain cancers but also offers avenues for novel treatment strategies. Advances in recombinant protein technology enable the production of functional TLX2, allowing for further investigations into its potential roles in tumorigenesis and stem cell maintenance, thus enhancing our understanding of its implications in cancer biology.
