关键信息
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基因名
ZBTB25
- 应用
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别名
ZBT25_HUMAN; ZBTB25; Zinc finger and BTB domain-containing Protein 25; Zinc finger Protein 46; Zinc finger Protein KUP
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P24278
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表达区间
1-435 aa
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氨基酸序列
MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGKSYRYNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQEHLDLPCALESELTQENVDTILVE
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分子量
73.37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ZBTB25, a member of the zinc finger and BTB domain-containing protein family, has garnered significant attention in recent years due to its pivotal roles in various biological processes and potential implications in disease. This protein is primarily involved in transcriptional regulation, influencing gene expression by interacting with specific DNA sequences and recruiting co-regulatory complexes. Research has shown that ZBTB25 plays essential roles in cellular differentiation, proliferation, and immune response, suggesting that its proper function is crucial for maintaining cellular homeostasis. Notably, aberrant expression of ZBTB25 has been associated with several pathological conditions, including cancers and autoimmune disorders, highlighting its potential as a therapeutic target. The study of recombinant ZBTB25 proteins has facilitated the understanding of its structure-function relationships and molecular mechanisms. By producing and characterizing these recombinant proteins, researchers aim to elucidate the signaling pathways in which ZBTB25 is involved, investigate its interactions with other proteins, and assess its regulatory effects on target genes. Such investigations are vital for developing novel therapeutic strategies that could intervene in diseases linked to ZBTB25 dysregulation, ultimately contributing to advancements in precision medicine and improved clinical outcomes.
