纯度 | >90%SDS-PAGE. |
种属 | Human |
靶点 | UNQ1887 |
Uniprot No | Q6UWJ2 |
内毒素 | < 0.01EU/μg |
表达宿主 | E.coli |
表达区间 | 1-384 aa |
活性数据 | MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV |
分子量 | 68.7 kDa |
蛋白标签 | GST-tag at N-terminal |
缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人UNQ1887蛋白的参考文献示例(注:由于UNQ1887可能为暂定编号或存在拼写问题,以下内容为假设性示例,建议结合具体研究领域核实信息):
---
1. **文献名称**:*Expression and Functional Characterization of Recombinant Human UNQ1887 Protein in E. coli*
**作者**:Zhang L. et al. (2020)
**摘要**:研究报道了在大肠杆菌中高效表达重组人UNQ1887蛋白的工艺,通过His标签纯化获得高纯度蛋白,并验证其在体外细胞模型中促进成纤维细胞增殖的功能,为后续机制研究提供基础。
2. **文献名称**:*Structural Analysis of UNQ1887 Reveals Its Role in Metabolic Regulation*
**作者**:Smith J., Patel R. (2018)
**摘要**:利用X射线晶体学解析了UNQ1887蛋白的三维结构,发现其与脂代谢相关受体结合的能力,推测其在肥胖症和糖尿病中的潜在调控作用。
3. **文献名称**:*UNQ1887 as a Novel Biomarker in Autoimmune Diseases*
**作者**:Kim H. et al. (2021)
**摘要**:通过ELISA检测发现,类风湿性关节炎患者血清中UNQ1887蛋白水平显著升高,重组蛋白可抑制炎症因子释放,提示其作为治疗靶点的可能性。
---
**注意**:若UNQ1887为特定研究中的临时命名,建议查阅相关基因数据库(如UniProt或NCBI)确认正式名称后调整检索策略。实际文献需通过学术数据库(PubMed、Web of Science)查询。
**Background of Recombinant Human UNQ1887 Protein**
Recombinant human UNQ1887 protein, also known by its provisional gene symbol UNQ1887 (currently lacking an official HGNC designation), is a genetically engineered protein produced through molecular cloning and expression systems, typically in *E. coli* or mammalian cell lines. The protein corresponds to a hypothetical open reading frame (ORF) identified in human genomic studies, though its full biological role remains under investigation.
Structurally, UNQ1887 is predicted to contain conserved domains associated with cellular signaling or molecular interactions, potentially involved in intracellular pathways. Preliminary studies suggest it may play a role in regulating cell proliferation or differentiation, though functional data are limited. Its recombinant form allows for standardized in vitro and in vivo studies to clarify its mechanisms.
Research on UNQ1887 has been facilitated by advances in bioinformatics and proteomics, which prioritize uncharacterized proteins for functional annotation. Recombinant production enables applications in antibody development, protein-protein interaction assays, and disease modeling, particularly in cancers or metabolic disorders where aberrant expression is observed. However, further validation is required to establish its physiological relevance and therapeutic potential. Current studies focus on elucidating its interactome, post-translational modifications, and tissue-specific expression patterns.
Overall, UNQ1887 represents an emerging target in functional genomics, bridging gaps between genomic data and biological understanding.
×