Cat: PAX2000-11148

Recombinant Human SCFD2 Protein,His

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关键信息

  • 基因名

    SCFD2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SCFD2; STXBP1L1; Sec1 family domain-containing protein 2; Syntaxin-binding protein 1-like 1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q8WU76

  • 表达区间

    1-684 aa

  • 氨基酸序列

    MSASGVLSFT QQGWEQVLAK VKRAVVYLDA ACAESLHWGC GSTRLLEAVG GPDCHLREFE PDAIGGGAKQ PKAVFVLSCL LKGRTVEILR DIICRSHFQY CVVVTTVSHA VHLTANHVPA AAAAEMEGQQ PVFEQLEEKL CEWMGNMNYT AEVFHVPLLL APVAPHFALT PAFASLFPLL PQDVHLLNSA RPDKRKLGSL GDVDSTTLTP ELLLQIRCLV SGLSSLCEHL GVREECFAVG SLSQVIAADL ANYAPAKNRK KTAAGRASVV FVDRTLDLTG AVGHHGDNLV EKIISALPQL PGHTNDVMVN MIALTALHTE EENYNVVAPG CLSQSSDTTA KALWEALLNT KHKEAVMEVR RHLVEAASRE NLPIKMSMGR VTPGQLMSYI QLFKNNLKAL MNHCGLLQLG LATAQTLKHP QTAKWDNFLA FERLLLQSIG ESAMSVVLNQ LLPMIKPVTQ RTNEDYSPEE LLILLIYIYS VTGELTVDKD LCEAEEKVKK ALAQVFCEES GLSPLLQKIT DWDSSINLTF HKSKIAVDEL FTSLRDIAGA RSLLKQFKSV YVPGNHTHQA SYKPLLKQVV EEIFHPERPD SVDIEHMSSG LTDLLKTGFS MFMKVSRPHP SDYPLLILFV VGGVTVSEVK MVKDLVASLK PGTQVIVLST RLLKPLNIPE LLFATDRLHP DLGF

  • 分子量

    75.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

SCFD2, a crucial protein in the plant immune system, belongs to the SCF (Skp1-Cullin-F-box) complex, which plays a vital role in ubiquitin-mediated degradation of proteins. This complex is pivotal for regulating various cellular processes, including growth, development, and responses to environmental stresses. Understanding the role of SCFD2 in plants can provide insights into how they defend against pathogens, particularly by modulating the stability of key immune regulators. Recent studies have highlighted the importance of SCFD2 in signaling pathways that activate defense responses, suggesting it is a potential target for enhancing disease resistance in crops. By utilizing techniques such as gene editing and proteomics, researchers aim to elucidate the molecular mechanisms underlying SCFD2 function. Ultimately, this knowledge could lead to the development of innovative strategies for improving plant resilience against biotic stress, addressing global food security challenges in the context of climate change and population growth.

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