关键信息
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基因名
ANGPTL1
- 应用
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别名
Angiopoietin like 1; ANGPTL1; ANG-3
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种属
Canine
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表达系统
HEK293
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标签
N-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A0A8C0RZS0
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表达区间
E197-D491
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蛋白长度
Partial
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分子量
64&38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ANGPTL1 (Angiopoietin-like 1) is a member of the angiopoietin-like protein family, which is known to play crucial roles in various physiological and pathological processes, including angiogenesis, metabolism, and inflammation. Its expression is prominent in various tissues, particularly in the cardiovascular system and adipose tissue, indicating its potential influence on metabolic disorders and cardiovascular diseases. Recent studies have shown that ANGPTL1 may modulate lipid metabolism by inhibiting lipoprotein lipase activity, which affects triglyceride levels in the bloodstream. This has spurred interest in ANGPTL1 as a potential therapeutic target for treating dyslipidemia and related conditions. Furthermore, research has indicated that ANGPTL1 may also possess anti-inflammatory properties, contributing to its protective role in cardiovascular health. The recombinant protein of ANGPTL1 is being utilized in exploratory studies to elucidate its biological functions, investigate its signaling pathways, and understand its interactions with other proteins. These efforts aim to establish a clearer understanding of ANGPTL1's role in health and disease, with implications for the development of novel therapeutic strategies in managing cardiovascular and metabolic disorders. Overall, the study of ANGPTL1 and its recombinant protein is positioned at the intersection of vascular biology and metabolic research, offering new insights into how this protein could be harnessed for clinical applications.
