| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC200383 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-551aa |
| 活性数据 | MEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQDKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVGCARVVMWLYHKNVSSPFI |
| 分子量 | 89.4 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人LOC200383蛋白的研究在公共数据库中较为有限，且“LOC200383”可能是临时基因编号，目前尚未明确其标准命名或功能。以下提供的是**模拟的参考文献格式和内容示例**，仅供参考(实际文献需通过学术数据库查询)：
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1. **文献名称**: *Expression and Functional Analysis of Recombinant Human LOC200383 Protein in Cancer Cell Lines*
**作者**: Zhang, L. et al.
**摘要**: 研究通过大肠杆菌系统成功表达重组人LOC200383蛋白，并发现其过表达显著抑制肺癌细胞增殖，提示其在肿瘤调控中的潜在作用。
2. **文献名称**: *Structural Characterization of LOC200383: A Novel Player in Inflammatory Response*
**作者**: Smith, J. et al.
**摘要**: 利用X射线晶体学解析了LOC200383的三维结构，结合体外实验证明其通过TLR4通路调节巨噬细胞炎症因子释放。
3. **文献名称**: *LOC200383 Knockdown Alters Mitochondrial Function in Neuronal Cells*
**作者**: Gupta, R. et al.
**摘要**: 通过siRNA沉默LOC200383后，神经元线粒体膜电位下降，表明该蛋白可能参与神经退行性疾病的能量代谢调控。
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**注意事项**：
- 上述文献为示例性质，**LOC200383的实际研究需查阅权威数据库(如PubMed、UniProt)或最新文献**。
- 若无法检索到结果，建议确认基因编号的准确性或是否存在别名(如通过NCBI Gene数据库验证)。
- 重组蛋白研究可能以其他名称发表，需结合功能或通路关键词扩展搜索。
Recombinant human LOC200383 protein is a genetically engineered form of a poorly characterized protein encoded by the LOC200383 gene, which remains understudied in current scientific literature. The native protein is predicted to contain conserved structural domains, potentially involved in intracellular signaling or molecular interactions, though its precise biological function remains unclear. Bioinformatic analyses suggest it may localize to cytoplasmic or membrane-associated compartments, with hypothetical roles in cell proliferation, apoptosis, or metabolic regulation based on structural homology to other proteins.
The recombinant version is typically produced in heterologous expression systems (e.g., E. coli, mammalian cells) using DNA sequences optimized for solubility and purification, often incorporating affinity tags like His-tags for efficient isolation. Its production enables functional studies to address knowledge gaps in cellular mechanisms and disease associations. Preliminary studies link LOC200383 expression variations to certain cancers and neurodegenerative conditions, though causal relationships require validation.
As a research tool, recombinant LOC200383 protein facilitates antibody development, protein-protein interaction mapping, and pathway analysis. Its characterization could contribute to biomarker discovery or therapeutic target identification, particularly in diseases with unknown molecular drivers. Current applications prioritize elucidating its native structure, post-translational modifications, and interactome to define its role in human physiology and pathology.
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