| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC161247 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-292aa |
| 活性数据 | MERGPVVGAGLGAGARIQALLGCLLKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRRSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGSPGHGLFPRPHSSRKHN |
| 分子量 | 58.6 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
由于目前公开的学术数据库中暂未收录关于“重组人LOC161247蛋白”的具体研究文献(截至2023年10月)，以下为基于典型重组蛋白研究模式的假设性参考文献框架。**实际使用前请通过权威数据库核实最新进展**：
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1. **文献名称**：*Expression and purification of recombinant human LOC161247 protein in E. coli*
**作者**：Li X, et al.
**摘要**：本研究成功构建了LOC161247蛋白的重组表达载体，利用大肠杆菌表达系统实现了蛋白的可溶性表达，并通过亲和层析纯化获得高纯度蛋白，为后续功能研究提供了材料基础。
2. **文献名称**：*LOC161247 interacts with inflammatory signaling pathways: insights from recombinant protein-based assays*
**作者**：Wang Y, et al.
**摘要**：通过体外实验发现，重组LOC161247蛋白能够抑制NF-κB通路的激活，提示其可能在调节炎症反应中发挥潜在作用，机制探索正在进行中。
3. **文献名称**：*Bioinformatic and structural characterization of the LOC161247 gene product*
**作者**：Zhang R, et al.
**摘要**：结合生物信息学分析预测LOC161247蛋白具有跨膜结构域，并成功通过哺乳动物细胞表达系统获得重组蛋白，晶体学分析揭示其可能的底物结合位点。
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**提示**：
- LOC编号(如LOC161247)通常为NCBI临时标识符，可能已被正式命名。建议通过NCBI Gene或UniProt查询最新基因名称(如可能为某个已知基因的别名)。
- 若需真实文献，可尝试检索相关功能关键词(如“重组蛋白表达”、“炎症调控蛋白”)结合最新数据库。
**Background of Recombinant Human LOC161247 Protein**
The human *LOC161247* gene, currently classified as a hypothetical or uncharacterized protein-coding gene, represents a relatively understudied component of the human genome. While its precise biological function remains unclear, *LOC161247* is believed to encode a protein potentially involved in cellular processes such as signaling, metabolism, or structural organization, based on computational predictions of its conserved domains and homology to proteins in other species. Recombinant human LOC161247 protein is artificially produced using biotechnological platforms (e.g., bacterial, yeast, or mammalian expression systems) to enable functional and structural studies.
Interest in this protein stems from the growing need to characterize unannotated genes and expand the map of functional human proteomes. Recombinant LOC161247 allows researchers to investigate its interactions, post-translational modifications, and subcellular localization, which could shed light on its role in health and disease. Preliminary studies may link it to disease pathways, though experimental validation is pending.
The development of recombinant LOC161247 also supports applications in antibody production, biomarker discovery, and high-throughput screening for drug development. Despite its current obscurity, elucidating its function could contribute to understanding molecular mechanisms underlying unexplained physiological or pathological conditions, highlighting the importance of exploring uncharacterized proteins in the human genome. Further research is essential to unlock its potential biomedical relevance.
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