关键信息
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基因名
IHPK2
- 应用
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别名
IHPK2；IHPK2；Inositol hexakisphosphate kinase 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UHH9
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表达区间
1-426aa
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氨基酸序列
MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQ FYETLPAEMRKFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVD NSDCEPKSKLLRWTTNKKHHVLETEKTPKDWVRQHRKEEKMKSHKLEEEF EWLKKSEVLYYTVEKKGNISSQLKHYNPWSMKCHQQQLQRMKENAKHRNQ YKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSA VIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAE DLEDLSEESADESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHE GQDAGYIFGLQSLIDIVTEISEESGEHHHHHHGGGLNDIFEAQKIEWHE
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分子量
52 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
IHPK2 (Inositol hexakisphosphate kinase 2) is a member of the inositol phosphates signaling pathway, which plays a crucial role in various cellular processes including cell growth, differentiation, and apoptosis. Increased understanding of IHPK2 has emerged due to its potential involvement in several diseases, particularly cancers and metabolic disorders. Research has indicated that IHPK2 functions as a regulatory enzyme converting inositol hexakisphosphate (InsP6) into inositol pyrophosphates, which are important signaling molecules within the cell. This pathway’s dysregulation has been linked to altered cellular responses and pathological conditions. Given its pivotal role in cell signaling, IHPK2 is being investigated for its potential as a therapeutic target. Moreover, the study of recombinant IHPK2 proteins facilitates the understanding of their biochemical properties and interactions. Characterizing these proteins can provide insights into their enzymatic functions and regulatory mechanisms, which is essential for developing novel therapeutic approaches. As the biochemical pathways involving inositol phosphates continue to be elucidated, IHPK2’s role could become increasingly significant in drug development and disease management strategies.
