关键信息
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基因名
CIB3
- 应用
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别名
CIB3；KIP3；Calcium and integrin-binding family member 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96Q77
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表达区间
1-187aa
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氨基酸序列
MGNKQTVFTH EQLEAYQDCT FFTRKEIMRL FYRYQDLAPQ LVPLDYTTCP DVKVPYELIG SMPELKDNPF RQRIAQVFSE DGDGHMTLDN FLDMFSVMSE MAPRDLKAYY AFKIYDFNND DYICAWDLEQ TVTKLTRGGL SAEEVSLVCE KVLDEADGDH DGRLSLEDFQ NMILRAPDFL STFHIRI
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分子量
21.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CIB3 (Calcium and Integrin Binding Protein 3) is an important member of the CIB protein family, known for its role in cellular calcium signaling and integrin modulation. The study of CIB3 has gained attention due to its potential involvement in various physiological processes and diseases, including erythropoiesis, immune responses, and cancer progression. Recent research has demonstrated that CIB3 can bind to calcium ions and interact with integrins, playing a crucial role in cell adhesion and migration. Understanding the structure and function of recombinant CIB3 proteins offers valuable insights into their biological roles and therapeutic potential. The recombinant production of CIB3 allows for detailed investigations into its interactions with other cellular components, providing a platform to explore its mechanism of action. Furthermore, studying CIB3 may open avenues for developing innovative therapeutic strategies targeting diseases where calcium signaling and integrin functions are disrupted. Given the increasing evidence of CIB3's involvement in critical cellular processes, ongoing research aims to elucidate its signaling pathways and potential as a therapeutic target, thereby deepening our understanding of its role in health and disease.
