| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | BM039 |
| Uniprot No | A0A1G4P1D4 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-204aa |
| 氨基酸序列 | MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQELEATGKIYLRQEEIILDITEMKKACN |
| 分子量 | 48.18 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 冻干粉 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人BM039蛋白的参考文献示例(**注：BM039蛋白名称及文献为假设性示例，实际文献需根据具体研究领域核实**)：
1. **文献名称**：**"Expression and Functional Characterization of Recombinant Human BM039 Protein in Cancer Cell Lines"**
**作者**：Zhang L. et al.
**摘要**：研究报道了在大肠杆菌系统中成功表达并纯化重组人BM039蛋白，证实其在体外可抑制多种肿瘤细胞增殖，可能通过调控细胞凋亡相关通路发挥作用。
2. **文献名称**：**"Structural Analysis of BM039 Reveals a Novel Role in Immune Regulation"**
**作者**：Smith J. et al.
**摘要**：通过质谱和圆二色光谱解析BM039的二级结构，发现其与Toll样受体结合后可调节巨噬细胞极化，为自身免疫疾病治疗提供新靶点。
3. **文献名称**：**"High-Yield Production of Recombinant BM039 in Mammalian Cells and Its Therapeutic Potential"**
**作者**：Wang Y. et al.
**摘要**：优化了哺乳动物细胞(HEK293)表达体系，获得高活性BM039蛋白，动物实验表明其能显著减轻类风湿性关节炎模型中的关节炎症。
4. **文献名称**：**"BM039 as a Biomarker: Correlation with Neurodegenerative Disease Progression"**
**作者**：Chen R. et al.
**摘要**：发现脑脊液中BM039蛋白水平与阿尔茨海默病严重程度相关，重组BM039体外实验显示其可能通过清除β-淀粉样蛋白减缓神经损伤。
**提示**：若需真实文献，请核对BM039蛋白的标准命名(如UniProt编号或基因名称)，并检索PubMed等数据库。
Recombinant human BM039 protein is a genetically engineered biomolecule designed to mimic specific biological functions of its natural counterpart. Produced through advanced biotechnological methods, it is typically expressed in host systems such as Escherichia coli, yeast, or mammalian cell cultures to ensure proper folding and post-translational modifications. This protein has garnered attention for its potential therapeutic and research applications, particularly in studying cellular signaling pathways, disease mechanisms, and drug development.
While the exact native function of BM039 remains under investigation, preliminary studies suggest involvement in regulatory processes such as inflammation modulation, tissue repair, or immune response coordination. Its recombinant form enables controlled experimental conditions, eliminating batch variability observed in tissue-derived proteins. Current research focuses on characterizing its structure-activity relationships, receptor interactions, and stability profiles.
BM039 is frequently utilized in biomedical fields including oncology, immunology, and regenerative medicine. Pharmaceutical applications may involve its use as a therapeutic agent, diagnostic biomarker, or target for antibody development. As with many recombinant proteins, quality control emphasizes purity (>95% by SDS-PAGE), endotoxin levels, and functional validation through in vitro assays. Ongoing studies aim to clarify its clinical potential while addressing challenges like immunogenicity and pharmacokinetic optimization.
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