Cat: IPD-X13971

Recombinant Pig FSH beta Protein, N- His & GST

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  • 规格
  • 数量

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关键信息

  • 基因名

    FSH beta

  • 应用

    SPR MST BLI ITC ELISA 细胞实验 药物筛选

  • 别名

    FSH-B; Follitropin Subunit Beta

  • 种属

    Pig

  • 表达系统

    E. coli

  • 标签

    N- His & GST

  • 纯度

    Greater than 85% as determined by SDS-PAGE.

  • 蛋白编号

    P01228

  • 表达区间

    Cys21~Glu129

  • 蛋白长度

    Partial

  • 分子量

    45kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Follicle-stimulating hormone (FSH) is a critical glycoprotein hormone involved in the regulation of reproductive processes in both males and females. It is synthesized in the anterior pituitary gland and plays a pivotal role in folliculogenesis in females and spermatogenesis in males. The hormone consists of two subunits, alpha and beta, with the beta subunit (FSHβ) being crucial for its biological activity and specificity. Research on recombinant FSHβ protein has gained significant attention due to its potential applications in reproductive health, infertility treatments, and assisted reproductive technologies. Advances in biotechnology enable the production of recombinant FSHβ, allowing for high purity and bioactivity, ultimately leading to improved clinical outcomes. Studies have shown that recombinant FSHβ can effectively stimulate ovarian stimulation protocols, enhance egg quality, and optimize in vitro fertilization (IVF) success rates. Additionally, this research explores the molecular mechanisms underlying FSH signaling pathways and their implications in various reproductive disorders. As a result, the development and characterization of recombinant FSHβ protein not only contribute to our understanding of hormonal regulation in reproduction but also pave the way for innovative therapeutic approaches in managing infertility and other reproductive health issues.

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