关键信息
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基因名
XCL2/SCM-1 beta
- 应用
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别名
SCYC2; SCM-1b; Small Inducible Cytokine Subfamily C Member 2; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBD3
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表达区间
Val22~Gly114
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蛋白长度
Partial
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分子量
42kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
XCL2, also known as SCM-1 beta, is a small cytokine belonging to the C chemokine family. It plays a crucial role in modulating immune responses, particularly in the attraction of lymphocytes to sites of inflammation and infection. The research surrounding XCL2/SCM-1 beta has gained momentum due to its implications in various autoimmune diseases, cancer, and viral infections. Elevated levels of this chemokine have been associated with disease progression, highlighting its potential as a biomarker for diagnostic and therapeutic purposes. Furthermore, XCL2's ability to selectively recruit lymphocytes, especially theC-C chemokine receptor type 4 (CCR4)-expressing T cells, positions it as a target for immunotherapeutic strategies. The production of recombinant XCL2/SCM-1 beta protein has become increasingly important for studying its biological functions, signaling pathways, and potential interactions with other immune modulators. This research not only elucidates the fundamental mechanisms of immune regulation but also opens avenues for the development of novel therapeutic interventions aimed at modulating the immune response in various pathological conditions.
