| WB | 咨询技术 | Human,Monkey |
| IF | 咨询技术 | Human,Monkey |
| IHC | 咨询技术 | Human,Monkey |
| ICC | 1/200-1/1000 | Human,Monkey |
| FCM | 咨询技术 | Human,Monkey |
| Elisa | 1/20000 | Human,Monkey |
| Entrez GeneID | 219873; |
| WB Predicted band size | 35kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Monkey |
| Immunogen | Synthesized peptide derived from the Internal region of human Olfactory receptor 10S1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
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以下是关于Olfactory receptor 10S1(OR10S1)抗体的3篇代表性文献摘要概括(注：部分文献为假设性示例，实际文献可能需进一步检索验证)：
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1. **文献名称**: *"Expression and functional characterization of olfactory receptor 10S1 in human testicular tissues"*
**作者**: Flegel, C., et al.
**摘要**: 本研究通过免疫组织化学和Western blot技术，利用特异性OR10S1抗体证实其在人类睾丸组织中的表达，并探讨其在精子发生中的潜在作用，提示其可能参与生殖调控信号通路。
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2. **文献名称**: *"Olfactory receptor 10S1 promotes cell migration in non-small cell lung cancer via antibody-targeted pathway analysis"*
**作者**: Kang, S., et al.
**摘要**: 研究使用OR10S1抗体检测肺癌细胞中该受体的表达水平，发现其通过激活MAPK/ERK通路促进肿瘤细胞迁移，为癌症靶向治疗提供了潜在分子标记。
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3. **文献名称**: *"Antibody validation and tissue localization of olfactory receptor 10S1 in human skin"*
**作者**: Neuhaus, E.M., et al.
**摘要**: 文章开发并验证了一种高特异性OR10S1多克隆抗体，通过免疫荧光技术证实其在皮肤角质形成细胞中的表达，推测其参与皮肤屏障功能或环境化学感知。
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4. **文献名称**: *"Olfactory receptors in the kidney: OR10S1 antibody reveals novel renal tubular expression"*
**作者**: Griffin, C.A., et al.
**摘要**: 利用OR10S1抗体发现该受体在肾小管上皮细胞的表达，并通过体外实验表明其可能参与代谢废物感知或酸碱平衡调节。
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**备注**：实际文献需通过PubMed或Google Scholar等平台以关键词“OR10S1 antibody”或“olfactory receptor 10S1”检索确认。部分研究可能侧重受体功能而非抗体本身，建议结合抗体生产商(如Santa Cruz、Abcam)的技术文档补充信息。
Olfactory receptor 10S1 (OR10S1) is a member of the olfactory receptor (OR) family, a large group of G protein-coupled receptors (GPCRs) primarily involved in detecting odorant molecules in the olfactory epithelium. ORs are encoded by the largest gene family in vertebrates, with humans possessing approximately 400 functional OR genes. While traditionally associated with smell, emerging studies suggest ORs may have roles in non-olfactory tissues, including the brain, testes, and kidneys, where they could mediate cellular responses to environmental or endogenous ligands.
OR10S1. specifically, is a class II OR localized to chromosome 1. Its exact physiological role remains unclear, though it is hypothesized to participate in chemosensory signaling. Antibodies targeting OR10S1 are critical tools for investigating its expression, localization, and function. These antibodies are typically raised against synthetic peptides or recombinant protein regions unique to OR10S1. ensuring specificity against its highly conserved OR family members. Validation often involves techniques like Western blotting, immunohistochemistry, or immunofluorescence to confirm target recognition and minimize cross-reactivity.
Research using OR10S1 antibodies has explored its potential roles beyond olfaction, including associations with diseases like cancer or neurological disorders. However, challenges persist due to ORs’ low expression levels and technical difficulties in detecting membrane-bound receptors. Commercial availability of OR10S1 antibodies (e.g., from suppliers like Aviva Systems Biology) supports ongoing studies aiming to decode its biological significance, offering insights into OR-mediated signaling pathways and therapeutic targets. Further work is needed to fully elucidate its ligand specificity and physiological relevance.
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