Rabbit Polyclonal Emp Antibody

The EMP antibody, primarily associated with autoimmune disorders, targets endometrial tissue components, particularly in conditions like endometriosis and infertility. Endometrial antibodies (EMP) are autoantibodies produced when the immune system mistakenly recognizes endometrial proteins as foreign, often due to retrograde menstruation or chronic inflammation. This aberrant immune response is linked to endometriosis, where ectopic endometrial tissue triggers systemic inflammation and antibody production. Elevated EMP levels correlate with compromised endometrial receptivity, implantation failure, and recurrent pregnancy loss, suggesting their role in immune-mediated reproductive dysfunction. Clinically, EMP detection aids in diagnosing unexplained infertility or autoimmune-related endometriosis subtypes. Research also explores their interaction with cytokines and growth factors, potentially disrupting endometrial remodeling and embryo adhesion. Current management includes immunosuppressive therapies or assisted reproductive techniques to bypass antibody-mediated damage. However, EMP's exact pathogenic mechanisms remain under investigation, with ongoing studies focusing on their molecular targets and utility as biomarkers for personalized treatment strategies in reproductive immunology.