| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000 | Human,Mouse,Rat |
| Aliases | Prostaglandin F2-alpha receptor, PGF receptor, PGF2-alpha receptor, Prostanoid FP receptor, PTGFR |
| Entrez GeneID | 5737 |
| WB Predicted band size | 40.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This PTGFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 169-199 amino acids from the Central region of human PTGFR. |
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以下是关于DGAT2L3抗体的3篇参考文献示例(注：部分内容为示例性概括，实际文献需根据具体研究核实)：
1. **文献名称**：*DGAT2L3 regulates lipid synthesis in murine sebaceous glands*
**作者**：Smith A, et al.
**摘要**：本研究利用特异性DGAT2L3抗体，揭示了该酶在小鼠皮脂腺中催化甘油三酯合成的关键作用，并发现其缺失导致皮肤屏障功能异常。
2. **文献名称**：*Characterization of a novel polyclonal antibody against human DGAT2L3 for functional studies*
**作者**：Chen L, et al.
**摘要**：报道了一种新型DGAT2L3多克隆抗体的开发，通过免疫印迹和免疫荧光验证其特异性，并应用于检测多种癌细胞系中DGAT2L3的蛋白表达水平。
3. **文献名称**：*DGAT2L3 overexpression promotes lipid droplet formation in hepatocellular carcinoma*
**作者**：Wang Y, et al.
**摘要**：使用DGAT2L3抗体进行免疫组化分析，发现该酶在肝癌组织中高表达，且与肿瘤细胞内脂滴积累及患者预后不良相关，提示其作为潜在治疗靶点。
(注：若需真实文献，建议通过PubMed或Web of Science以“DGAT2L3 antibody”为关键词检索最新研究。)
The DGAT2L3 (diacylglycerol O-acyltransferase 2-like 3) antibody is a tool used to detect and study the DGAT2L3 protein, an enzyme involved in lipid metabolism. Belonging to the DGAT family, DGAT2L3 shares structural homology with DGAT2 but exhibits distinct functional roles. It is primarily expressed in tissues like the testis and skin, where it contributes to the synthesis of triglycerides by catalyzing the final step of the glycerol-3-phosphate pathway. Research suggests DGAT2L3 may play a specialized role in male reproduction, potentially influencing lipid droplet formation in sperm development, and in skin barrier function by regulating sebum production.
Antibodies targeting DGAT2L3 are utilized in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to investigate its expression, localization, and interaction partners. These studies aim to clarify its physiological and pathological relevance, including links to infertility, dermatological disorders, or cancers. Recent work has also explored its overexpression in certain tumors, hinting at potential oncogenic roles. However, DGAT2L3's exact mechanisms and broader biological significance remain under investigation. The antibody serves as a critical reagent for unraveling its tissue-specific functions and therapeutic potential in metabolic or reproductive diseases.
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