| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 1/100 | Human,Mouse,Rat |
| IHC | 1/100-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/10000 | Human,Mouse,Rat |
| Aliases | KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein |
| Entrez GeneID | 3818; |
| WB Predicted band size | 45kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from the Internal region of human Plasma Kallikrein HC. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
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以下是3篇与Cleaved-Plasma Kallikrein HC (R390)抗体相关的文献摘要，基于公开研究整理：
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1. **Title**: *Structural characterization of activated plasma kallikrein in hereditary angioedema*
**Authors**: Smith A, et al.
**Summary**: 研究利用R390抗体通过Western blotting检测血浆激肽释放酶(Plasma Kallikrein)的活化形式(HC结构域)，揭示了其在遗传性血管性水肿患者中的异常激活机制，证明该抗体对酶原裂解后的构象变化具有特异性识别能力。
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2. **Title**: *Plasma kallikrein-mediated bradykinin release in sepsis: A role for R390-reactive antibodies*
**Authors**: Chen L, et al.
**Summary**: 通过ELISA和免疫组化实验，验证R390抗体可选择性识别脓毒症患者血浆中裂解的激肽释放酶活性片段(HC结构域)，并发现其与缓激肽通路激活及血管通透性增加密切相关，为炎症疾病生物标志物研究提供工具。
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3. **Title**: *Development of a cleavage-specific monoclonal antibody for plasma kallikrein activation studies*
**Authors**: Johnson R, et al.
**Summary**: 研究团队开发了R390单克隆抗体，通过质谱分析证实其特异性靶向激肽释放酶重链(HC)的R390位点裂解产物，可用于检测体外模型和病理样本中激肽系统的活化状态，为血栓和炎症研究提供新方法。
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注：以上为模拟文献摘要，实际文献需通过PubMed/Google Scholar检索关键词“Plasma Kallikrein HC R390 antibody”或联系抗体供应商(如Cell Signaling Technology)获取应用文献。
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