Rabbit Polyclonal OSR2 Antibody

The OSR2 antibody is designed to target the Odd-skipped related 2 (OSR2) protein, a transcription factor belonging to the Odd-skipped/SALL family. OSR2 is evolutionarily conserved and plays critical roles in embryonic development, particularly in organogenesis, limb patterning, and craniofacial morphogenesis. It regulates gene expression by binding to specific DNA sequences via its zinc finger domains, influencing cell differentiation and tissue organization. Studies in model organisms, such as mice, highlight its importance in kidney development, palate formation, and skeletal growth. Dysregulation of OSR2 has been linked to developmental disorders and diseases, including cancers and fibrosis. The OSR2 antibody is widely used in research to detect protein expression and localization in tissues or cells via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It aids in elucidating OSR2's molecular mechanisms, such as its interplay with signaling pathways like Wnt or BMP, and its role in epithelial-mesenchymal transitions. Researchers also employ this antibody to explore OSR2's potential as a biomarker or therapeutic target in pathological conditions. Its specificity and reliability make it a valuable tool in developmental biology, oncology, and regenerative medicine studies.