关键信息
-
基因名
MRPL2
- 应用
-
别名
MRPL2;Large ribosomal subunit Protein uL2m
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q5T653
-
表达区间
84-202aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSGRDHTGR IRVHGIGGGH KQRYRMIDFL RFRPEETKSG PFEEKVIQVR YDPCRSADIA LVAGGSRKRW IIATENMQAG DTILNSNHIG RMAVAAREGD AHPLGALPVG TLINNVESEP GR
-
分子量
16 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MRPL2 (Mitochondrial Ribosomal Protein L2) is a crucial component of the mitochondrial ribosome, playing a pivotal role in mitochondrial protein synthesis and the overall functionality of mitochondria. Mitochondria are essential organelles responsible for energy production, cellular metabolism, and regulation of apoptotic pathways. Dysregulation or mutations in mitochondrial proteins, including MRPL2, can lead to various mitochondrial diseases, which often manifest as metabolic disorders, neurodegeneration, and other serious health conditions. The study of MRPL2 recombinant proteins is vital for understanding its structure-function relationship and its role in mitochondrial biogenesis and homeostasis. By producing recombinant MRPL2, researchers can investigate its biochemical properties, interactions with other mitochondrial components, and the impact of specific mutations on its activity. This research can also provide insights into potential therapeutic targets for mitochondrial diseases. Furthermore, recombinant MRPL2 can be utilized in studies exploring protein expression, folding, and the mechanisms underlying mitochondrial translation, thereby deepening our understanding of mitochondrial dynamics and their implications in human health and disease. Overall, the investigation of MRPL2 through recombinant protein studies is a significant step towards elucidating the complexities of mitochondrial functions and their contributions to cellular health.
