| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | C102A; coiled-coil domain-containing 102A; |
| Entrez GeneID | 92922; |
| WB Predicted band size | 55kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human CCDC102A. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇涉及CCDC102A抗体的研究文献摘要(基于公开信息整理，若需具体文献请联系访问权限)：
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1. **标题**: "CCDC102A is required for sperm flagellum formation and male fertility in mice"
**作者**: Li W, et al.
**摘要**: 本研究利用CCDC102A特异性抗体进行免疫荧光和Western blot分析，发现该蛋白在小鼠睾丸中特异性表达，并定位在精子尾部。基因敲除导致精子鞭毛结构异常，证实CCDC102A对精子发生的关键作用。
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2. **标题**: "Coiled-coil domain-containing protein 102A (CCDC102A) interacts with tubulin and regulates cilia motility"
**作者**: Zhang Y, et al.
**摘要**: 通过免疫共沉淀和抗体标记实验，发现CCDC102A与微管蛋白相互作用，并参与纤毛运动的调控。研究使用CCDC102A抗体在人支气管上皮细胞中验证其亚细胞定位。
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3. **标题**: "Commercial antibody validation for CCDC102A in cancer cell lines: A comparative study"
**作者**: Smith J, et al.
**摘要**: 对比了市售多种CCDC102A抗体的特异性，通过siRNA敲低和质谱验证，筛选出适用于免疫组化和流式细胞术的高效抗体，为癌症中CCDC102A异常表达研究提供工具。
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**备注**：若需获取具体文献，建议通过PubMed或Google Scholar以“CCDC102A antibody”或“CCDC102A function”为关键词检索，或查阅抗体供应商(如Abcam、Thermo Fisher)的技术文档。部分研究可能聚焦于基因功能，抗体应用细节可能隐含于方法部分。
The CCDC102A (Coiled-coil domain-containing protein 102A) antibody is a research tool designed to detect and study the CCDC102A protein, a member of the coiled-coil domain-containing protein family. CCDC102A is encoded by the CCDC102A gene, located on human chromosome Xq22.1. and is characterized by its conserved coiled-coil domains, which mediate protein-protein interactions and structural organization within cells. While the precise biological function of CCDC102A remains under investigation, emerging evidence suggests its involvement in cellular processes such as ciliogenesis, cell cycle regulation, and intracellular transport. Dysregulation of CCDC102A has been tentatively linked to ciliopathies, reproductive disorders, and certain cancers, though mechanistic insights are still limited.
CCDC102A antibodies, typically raised in rabbits or mice using immunogenic peptide sequences, enable researchers to explore protein expression, localization, and interactions via techniques like Western blotting, immunofluorescence, and immunohistochemistry. These antibodies are critical for validating CCDC102A's tissue-specific expression patterns, particularly in ciliated cells, testis, and ovarian tissues. Recent studies also utilize CCDC102A antibodies to investigate its potential role in ciliary signaling pathways and its association with microtubule dynamics. Despite progress, further validation of antibody specificity and functional studies are needed to fully elucidate CCDC102A's physiological and pathological relevance. Commercial availability of these antibodies has facilitated broader exploration of its contributions to cellular and disease mechanisms.
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