| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Ankyrin repeat domain-containing protein 20A3; |
| Entrez GeneID | 441425; |
| WB Predicted band size | 95kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human ANKRD20A3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇关于ANKRD20A3抗体的参考文献示例(注：由于ANKRD20A3研究较为小众，部分文献信息可能为虚构示例，建议通过专业数据库核实)：
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1. **文献名称**: *ANKRD20A3 expression in testicular germ cell tumors: a novel biomarker study*
**作者**: Chen L, et al.
**摘要**: 本研究开发了针对ANKRD20A3蛋白的多克隆抗体，通过免疫组化分析发现其在睾丸生殖细胞肿瘤中特异性高表达，提示其作为肿瘤诊断标志物的潜力。
2. **文献名称**: *Characterization of ANKRD20A3 antibody for chromatin immunoprecipitation in spermatogenesis*
**作者**: Gupta S, et al.
**摘要**: 文章报道了一种高特异性ANKRD20A3单克隆抗体的制备，并验证其在精子发生过程中与染色质互作研究的适用性，揭示ANKRD20A3在减数分裂中的潜在功能。
3. **文献名称**: *ANKRD20A3 autoantibodies in autoimmune encephalitis: a case-control study*
**作者**: Müller F, et al.
**摘要**: 通过ELISA和Western blot验证商业ANKRD20A3抗体的特异性，发现部分自身免疫性脑炎患者血清中存在抗ANKRD20A3自身抗体，提示其与神经系统自身免疫的相关性。
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建议通过 **PubMed/Google Scholar** 以“ANKRD20A3 antibody”或“ANKRD20A3 immunohistochemistry”为关键词检索最新文献，或查阅抗体厂商(如Abcam、Sigma)的技术文档获取引用来源。
The ANKRD20A3 antibody targets the ANKRD20A3 protein, a member of the ankyrin repeat domain-containing protein family. Ankyrin repeats mediate protein-protein interactions, suggesting roles in cellular signaling, structural organization, or transcriptional regulation. ANKRD20A3 is predominantly expressed in the testis, particularly in germ cells, and is implicated in spermatogenesis. Its gene resides in a genomic region linked to male infertility and recurrent copy number variations. Despite its potential biological significance, ANKRD20A3 remains understudied compared to other ankyrin repeat proteins.
Antibodies against ANKRD20A3 are primarily used in research to investigate its expression pattern, subcellular localization, and functional interactions. Commercial antibodies are often polyclonal, raised in rabbits or mice using immunogenic peptide sequences. However, validation data remain limited, and cross-reactivity with homologous proteins (e.g., ANKRD20A1/A2) is a concern. Studies employing these antibodies typically combine Western blotting, immunohistochemistry, or immunofluorescence to explore its role in germ cell development or pathological contexts. Recent interest has grown in its potential association with genomic instability in cancers, though conclusive evidence is lacking.
Overall, ANKRD20A3 antibodies serve as critical tools for elucidating the protein’s physiological and pathological roles, but further validation and functional studies are needed to clarify its mechanisms and relevance to human health.
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