关键信息
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基因名
MDP1
- 应用
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别名
DPEP1;MDP;RDP;Dipeptidase 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86V88
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表达区间
1-176aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMARLPKLAVFDLDYTLWPFWVDTHVD PPFHKSSDGTVRDRRGQDVRLYPEVPEVLKRLQSLGVPGAAASRTSEIEG ANQLLELFDLFRYFVHREIYPGSKITHFERLQQKTGIPFSQMIFFDDERR NIVDVSKLGVTCIHIQNGMNLQTLSQGLETFAKAQTGPLRSSLEESPFEA
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MDP1 (Myelin Differentiation Protein 1) is a crucial protein involved in the formation and maintenance of myelin, the protective sheath surrounding nerve fibers, which is essential for proper neuronal function and signal transmission. Abnormalities in myelination processes are associated with various neurological disorders, including multiple sclerosis and leukodystrophies. The study of MDP1 and its recombinant proteins has gained significant interest in recent years due to its potential therapeutic implications. Researchers aim to understand the structure-function relationship of MDP1, its role in oligodendrocyte development, and the signaling pathways it influences. Additionally, recombinant MDP1 can be utilized in experimental models to investigate myelination and demyelination mechanisms, providing insights into potential regenerative therapies for nervous system injuries. Current studies are focusing on optimizing the production and characterization of MDP1 recombinant proteins to facilitate their use in both basic research and clinical applications. By elucidating the biochemical properties and interactions of MDP1, scientists hope to identify novel targets for therapeutic intervention in demyelinating diseases, ultimately leading to the development of effective treatments that can enhance myelin repair and improve neurological outcomes.
