Rabbit Polyclonal MRPL24 Antibody

The MRPL24 antibody is a research tool designed to detect mitochondrial ribosomal protein L24 (MRPL24), a component of the mitochondrial ribosome's large subunit (39S). MRPL24 plays a critical role in mitochondrial protein synthesis, which is essential for oxidative phosphorylation and cellular energy production. As part of the mitochondrial translation machinery, MRPL24 contributes to ribosome assembly, stability, or catalytic function, though its exact molecular role remains under investigation. Antibodies targeting MRPL24 are widely used in immunoblotting (Western blot), immunofluorescence, or immunohistochemistry to study mitochondrial ribosome composition, biogenesis, and dysfunction linked to diseases such as mitochondrial disorders, neurodegenerative conditions, or cancer. These antibodies help researchers assess MRPL24 expression levels, subcellular localization, or interactions in cell lines, tissues, or disease models. Commercial MRPL24 antibodies are typically raised in hosts like rabbits or mice, with validation data including specificity checks (e.g., knockdown controls) and cross-reactivity information. Their application advances understanding of mitochondrial translation defects, metabolic regulation, and pathologies associated with mitochondrial DNA mutations or ribosomal stress. Proper controls are necessary to ensure specificity due to potential homology with cytoplasmic ribosomal proteins.