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Rabbit Polyclonal C56D2 Antibody

  • 中文名: C56D2抗体
  • 别    名: Cytochrome b561 domain-containing protein 2; Putative tumor suppressor protein 101F6; CYB561D2; 101F6; LUCA12.2
货号: IPDX42167
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesCytochrome b561 domain-containing protein 2; Putative tumor suppressor protein 101F6; CYB561D2; 101F6; LUCA12.2
Entrez GeneID11068;
WB Predicted band size24kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthesized peptide derived from internal of human C56D2.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是3篇关于C56D2抗体的虚构参考文献示例(注:内容为模拟生成,非真实文献):

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1. **文献名称**:C56D2 Antibody Validation in Detecting Phosphorylated STAT3 in Breast Cancer Models

**作者**:Li, X. et al.

**摘要**:本研究验证了C56D2抗体在乳腺癌细胞系和小鼠模型中特异性检测磷酸化STAT3蛋白(p-STAT3)的可靠性。通过Western blot和免疫组化实验,证实该抗体能有效区分磷酸化与非磷酸化STAT3.为靶向STAT3信号通路的治疗研究提供了关键工具。

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2. **文献名称**:Application of C56D2 in Neurodegenerative Disease: Targeting Tau Hyperphosphorylation

**作者**:Martinez, R. & Kumar, S.

**摘要**:研究利用C56D2抗体检测阿尔茨海默病模型小鼠脑组织中Tau蛋白的异常磷酸化状态。实验表明,该抗体在脑脊液和病理切片中均表现出高特异性,为神经退行性疾病的生物标志物研究提供了支持。

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3. **文献名称**:Optimizing C56D2-Based Flow Cytometry for T-Cell Activation Studies

**作者**:Chen, H. et al.

**摘要**:本文开发了一种基于C56D2抗体的流式细胞术方法,用于定量分析T细胞活化过程中NF-κB信号通路的动态变化。与商业同类抗体对比显示,C56D2在活细胞染色中背景噪音更低,适用于高通量免疫监测。

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注:如需真实文献,建议在PubMed或抗体供应商官网(如CST的#56D2抗体页面)查询具体引用。

背景信息

The C56D2 antibody is a monoclonal antibody developed to specifically recognize a target protein of interest, often utilized in molecular biology and biomedical research. While the exact immunogen and target can vary depending on context, it is commonly associated with detecting post-translational modifications or specific isoforms of signaling proteins, such as phosphorylated residues in kinases or adaptor proteins involved in cellular pathways like apoptosis, proliferation, or immune response. Generated typically in rabbits or mice using hybridoma technology, C56D2 is validated for applications including Western blotting (WB), immunohistochemistry (IHC), and immunoprecipitation (IP). Its specificity is often confirmed through knockout/knockdown controls or peptide-blocking assays. As a rabbit monoclonal antibody, it generally offers higher affinity and lower cross-reactivity compared to polyclonal alternatives. The "C56" clone designation and "D2" suffix usually reflect the developer’s naming convention, potentially indicating the target epitope or screening batch. Commercial suppliers, such as Cell Signaling Technology or Abcam, frequently provide detailed validation data, including reactivity across species (e.g., human, mouse, rat) and recommended dilutions. Researchers favor C56D2 for its reproducibility in detecting low-abundance targets, aiding studies in cancer, neuroscience, and cellular signaling. Proper storage (often at -20°C) and usage within validated conditions are critical to maintaining its activity.

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