Cat: PA1000-1882

Recombinant Human MAK16 Protein,His

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关键信息

  • 基因名

    MAK16

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    MAK16;RBM13;Protein MAK16 homolog

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9BXY0

  • 表达区间

    1-300aa

  • 氨基酸序列

    MQSDDVIWDT LGNKQFCSFK IRTKTQSFCR NEYSLTGLCN RSSCPLANSQ YATIKEEKGQ CYLYMKVIER AAFPRRLWER VRLSKNYEKA LEQIDENLIY WPRFIRHKCK QRFTKITQYL IRIRKLTLKR QRKLVPLSKK VERREKRREE KALIAAQLDN AIEKELLERL KQDTYGDIYN FPIHAFDKAL EQQEAESDSS DTEEKDDDDD DEEDVGKREF VEDGEVDESD ISDFEDMDKL DASSDEDQDG KSSSEEEEEK ALSAKHKGKM PLRGPLQRKR AYVEIEYEQE TEPVAKAKTT

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

MAK16 is a novel protein that has garnered significant interest in the field of molecular biology and biochemistry due to its crucial role in various cellular processes. Research indicates that MAK16 is involved in regulating gene expression and RNA metabolism, which are vital for maintaining cellular homeostasis and function. It was initially identified through genomic studies aimed at understanding the complex interplay between proteins and RNA in eukaryotic cells. Further investigations revealed that MAK16 is associated with ribonucleoprotein complexes, suggesting its involvement in ribosome biogenesis and RNA splicing. This protein has been linked to several cellular pathways that are critical for cell proliferation and differentiation. Moreover, aberrations in MAK16 expression have been associated with several diseases, including cancer and neurodegenerative disorders, highlighting its potential as a biomarker for disease progression and as a therapeutic target. As researchers continue to explore the structural and functional characteristics of MAK16, it opens new avenues for understanding the molecular mechanisms underlying cellular dysfunction. Overall, the study of MAK16 not only enriches our knowledge of cellular machinery but also paves the way for innovative approaches in treating various diseases linked to dysregulation of RNA processes.

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