| WB | 1/500-1/3000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24; PEG3; KIAA0287; ZSCAN24 |
| Entrez GeneID | 5178; |
| WB Predicted band size | 181kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human PEG3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于PEG3抗体的3篇示例参考文献(注：文献为假设示例，实际引用需核实真实来源)：
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1. **文献名称**：*"PEG3 Antibody Development and Its Application in Detecting Tumor Suppression Activity"*
**作者**：Kim J. et al.
**摘要**：研究团队开发了一种高特异性的PEG3多克隆抗体，通过Western blot和免疫组化验证其在多种癌细胞系中的表达，发现PEG3低表达与肿瘤侵袭性相关，提示其潜在抑癌功能。
2. **文献名称**：*"Paternally Expressed Gene 3 (PEG3) in Neural Development: Insights from Immunohistochemical Analysis"*
**作者**：Li X. et al.
**摘要**：利用PEG3抗体进行小鼠脑组织免疫染色，发现PEG3在发育中神经元的特定区域(如下丘脑)高表达，提示其对神经分化和突触形成的调控作用。
3. **文献名称**：*"Epigenetic Regulation of PEG3 in Ovarian Cancer: A Diagnostic Biomarker Study"*
**作者**：Smith R. et al.
**摘要**：通过新型PEG3单克隆抗体检测卵巢癌组织样本，发现PEG3启动子甲基化导致蛋白表达缺失，可能作为早期诊断及预后评估的标志物。
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如需真实文献，建议通过PubMed或Google Scholar搜索关键词“PEG3 antibody”、“PEG3 biomarker”或结合具体研究领域(如癌症、表观遗传学)筛选近年研究。
**Background of PEG3 Antibody**
The PEG3 (Paternally Expressed Gene 3) antibody is a tool used to detect the PEG3 protein, encoded by an imprinted gene located on human chromosome 19q13.4. PEG3 is maternally silenced and paternally expressed, playing critical roles in embryonic development, cell proliferation, and apoptosis regulation. It belongs to the zinc-finger protein family, functioning as a transcriptional regulator that influences downstream genes involved in growth and stress responses.
Research highlights PEG3's involvement in tumorigenesis and cancer progression, with aberrant expression observed in cancers such as glioblastoma, breast cancer, and ovarian cancer. It is also linked to neurological functions and placental development, underscoring its importance in developmental biology.
PEG3 antibodies are widely utilized in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study protein expression patterns, subcellular localization, and interactions in both normal and diseased tissues. These antibodies aid in exploring PEG3's dual role as a tumor suppressor or oncogene, depending on cellular context, and its potential as a biomarker for cancer prognosis. Additionally, they contribute to epigenetic studies, particularly in understanding genomic imprinting mechanisms and their impact on development and disease.
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