关键信息
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基因名
EFNB2A
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简介
The EFNB2A protein is a cell surface ligand of the Eph receptor that critically regulates migration, repulsion, and adhesion in neuronal, vascular, and epithelial development. EFNB2A Protein, zebrafish (HEK293, Fc) is the recombinant EFNB2A protein, expressed by HEK293 , with C-hFc labeled tag.
- 应用
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别名
Ephrin-B2a; efnb2
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种属
Others
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表达系统
HEK293
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标签
C-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O73874
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表达区间
L25-A222
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蛋白长度
Extracellular Domain
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分子量
97 kDa & 58 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of EFNB2A, a member of the ephrin family, has garnered significant attention in the fields of neurobiology and cancer research due to its crucial roles in cell signaling, development, and tissue patterning. Ephrins are glycoproteins that interact with ephrin receptors to mediate various biological processes, including neuronal development, angiogenesis, and immune responses. EFNB2A, specifically, has been implicated in the regulation of neuronal axon guidance and synaptic plasticity, making it a key player in brain development and function. Moreover, emerging evidence suggests that aberrations in EFNB2A signaling pathways may contribute to tumorigenesis and metastasis in various cancers, indicating its potential as a therapeutic target. Researchers are particularly interested in the recombinant expression of EFNB2A to elucidate its functional properties and interactions with receptors, which could lead to advanced understanding of its roles in health and disease. Through detailed studies of EFNB2A, scientists aim to uncover its potential applications in regenerative medicine and cancer treatment, paving the way for novel therapeutic strategies.
