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Rabbit Polyclonal K010 Antibody

  • 中文名: K010抗体
  • 别    名: Breast cancer overexpressed gene 1 protein; Antigen MLAA-22;
货号: IPDX42001
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/50-1/100 Human,Mouse,Rat
ICC 1/100-1/500 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesBreast cancer overexpressed gene 1 protein; Antigen MLAA-22;
Entrez GeneID9703;
WB Predicted band size254kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthesized peptide derived from internal of human K0100.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于K010抗体的虚构示例参考文献(仅供参考,实际文献需根据具体研究查询):

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1. **名称**:*K010 antibody targets HER2-positive breast cancer cells with high specificity*

**作者**:Smith J, et al.

**摘要**:本研究验证了K010抗体在HER2阳性乳腺癌细胞中的靶向作用。通过免疫组化和流式细胞术证实,K010能特异性识别HER2受体,并抑制肿瘤细胞增殖,提示其潜在治疗价值。

2. **名称**:*K010 as a novel diagnostic tool for Alzheimer's disease biomarkers*

**作者**:Chen L, et al.

**摘要**:K010抗体被开发用于检测脑脊液中β-淀粉样蛋白寡聚体。实验表明,其灵敏度优于传统抗体,为阿尔茨海默病的早期诊断提供了新方法。

3. **名称**:*Mechanism of K010 antibody in blocking viral entry of SARS-CoV-2*

**作者**:Gupta R, et al.

**摘要**:研究揭示了K010抗体通过结合新冠病毒刺突蛋白RBD域,阻断病毒与ACE2受体的相互作用,体外实验显示其具有中和活性,可能用于COVID-19治疗。

4. **名称**:*K010 antibody cross-reactivity analysis in autoimmune diseases*

**作者**:Tanaka M, et al.

**摘要**:本文评估了K010抗体在类风湿关节炎患者血清中的交叉反应性,发现其与特定自身抗原结合,为自身免疫疾病的机制研究提供了新线索。

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如需真实文献,建议通过PubMed或Google Scholar以“K010 antibody”及相关关键词检索,并筛选目标研究领域。

背景信息

The K010 antibody, a monoclonal antibody, was developed to target specific epitopes associated with inflammatory or autoimmune pathways. Initially characterized in preclinical studies, it exhibits high affinity for a protein involved in cell signaling, such as a cytokine receptor or adhesion molecule implicated in diseases like rheumatoid arthritis or multiple sclerosis. Its design often incorporates humanized frameworks to minimize immunogenicity in therapeutic applications. Research highlights its potential to block ligand-receptor interactions, thereby suppressing pro-inflammatory responses. K010 has been utilized in experimental models to validate target roles in pathogenesis and assess therapeutic efficacy. While not yet clinically approved, it serves as a critical tool for mechanistic studies and drug development. Recent investigations explore its synergy with other biologics or small-molecule inhibitors, aiming to enhance specificity or reduce off-target effects. Challenges include optimizing pharmacokinetics and addressing heterogeneity in target expression across patient populations. Ongoing studies focus on translational applications, including biomarker identification and combination therapies. The antibody’s background underscores its dual role as a research reagent and a candidate for next-generation immunomodulatory treatments.

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