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Rabbit Polyclonal GLPK3 Antibody

  • 中文名: GLPK3抗体
  • 别    名: Glycerol kinase; testis specific 1; EC 2.7.1.30; ATP:glycerol 3-phosphotransferase; Glycerokinase
货号: IPDX41999
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesGlycerol kinase; testis specific 1; EC 2.7.1.30; ATP:glycerol 3-phosphotransferase; Glycerokinase
Entrez GeneID2713;
WB Predicted band size61kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthesized peptide derived from internal of human GLPK3.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于GLPK3抗体的虚构参考文献示例(注:GLPK3可能并非标准术语,建议核实名称准确性):

1. **"Development of a Polyclonal Antibody Against GLPK3 for Glycogen Metabolism Studies"**

- **作者**: Smith A, et al.

- **摘要**: 描述了针对GLPK3的兔多克隆抗体的制备,通过Western blot和免疫组化验证其在肝组织中的特异性,用于研究糖原代谢调控机制。

2. **"GLPK3 Kinase Activity in Cell Cycle Regulation"**

- **作者**: Lee B, Chen C.

- **摘要**: 利用GLPK3抗体进行免疫沉淀实验,发现其在细胞周期调控中与CDK2相互作用,提示其可能参与G1/S期转换。

3. **"Antibody-Based Profiling of GLPK3 in Diabetic Mouse Models"**

- **作者**: Zhang X, et al.

- **摘要**: 应用GLPK3抗体分析糖尿病小鼠模型中的表达变化,发现GLPK3在胰岛素抵抗组织中上调,可能与代谢紊乱相关。

4. **"Validation of a Monoclonal GLPK3 Antibody for Cancer Research"**

- **作者**: Johnson R, et al.

- **摘要**: 开发并验证了一种高特异性单克隆抗体,用于检测多种癌症细胞系中GLPK3的异常表达,提示其潜在肿瘤标志物作用。

**注意**:以上文献为示例,实际研究中“GLPK3”可能并非标准命名,建议确认目标蛋白的正确名称(如GPK3、GRK3等)或相关通路,并检索PubMed/Google Scholar获取真实文献。

背景信息

The GLPK3 antibody is designed to target glycerol kinase 3 (GK3), an enzyme encoded by the *GK3* gene, which plays a role in glycerol metabolism by catalyzing the conversion of glycerol to glycerol-3-phosphate. This reaction is critical for cellular energy production and lipid biosynthesis. Glycerol kinase deficiencies are associated with metabolic disorders, making GK3 a subject of interest in metabolic disease research. The GLPK3 antibody is primarily used in biochemical assays, such as Western blotting, immunohistochemistry, and immunofluorescence, to detect GK3 expression levels in tissues or cell lines. Researchers employ it to study GK3's regulatory mechanisms, tissue-specific distribution, and potential involvement in conditions like hyperglycerolemia or mitochondrial dysfunction. Recent studies have also explored GK3's interaction with other metabolic enzymes, shedding light on its role in energy homeostasis. While GK3 is less characterized than its isoform GK1. the GLPK3 antibody serves as a vital tool for elucidating its biological functions and potential therapeutic implications in metabolic syndromes, obesity, or rare inherited disorders linked to glycerol kinase activity.

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