| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Probable ganciclovir kinase; EC=2.7.1.-; |
| Entrez GeneID | 1497069; |
| WB Predicted band size | 65kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human GCVK_HHV6Z. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于GCVK_HHV6Z抗体的3篇假设性参考文献示例(注：GCVK_HHV6Z可能为虚构命名，以下内容基于HHV-6抗体相关研究模拟)：
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1. **文献名称**：*Development of a Monoclonal Antibody GCVK_HHV6Z for Specific Detection of Human Herpesvirus 6 Latent Infection*
**作者**：Yamanishi, K., et al.
**摘要**：该研究报道了GCVK_HHV6Z单克隆抗体的开发，该抗体特异性靶向HHV-6的早期即刻蛋白IE1.用于检测病毒在宿主细胞中的潜伏感染，并在免疫组化分析中展现出高灵敏度和特异性。
2. **文献名称**：*GCVK_HHV6Z Antibody Neutralizes HHV-6B Infection in vitro and Reduces Viral Load in a Mouse Model*
**作者**：Ablashi, D., et al.
**摘要**：研究验证了GCVK_HHV6Z抗体通过结合HHV-6B的糖蛋白gH/gL复合体，在体外中和病毒活性，并在小鼠模型中显著降低病毒载量，提示其治疗HHV-6相关疾病的潜力。
3. **文献名称**：*Epitope Mapping of GCVK_HHV6Z Antibody and Its Cross-Reactivity with HHV-7*
**作者**：Pellett, P.E., et al.
**摘要**：通过表位定位分析，发现GCVK_HHV6Z靶向HHV-6的保守区域，但与HHV-7无交叉反应，为开发特异性诊断工具提供了分子基础。
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**说明**：以上文献为模拟示例，实际研究中可能存在命名差异。建议通过PubMed或Google Scholar以关键词“HHV-6 antibody”“glycoprotein”“monoclonal”等检索真实文献。
The GCVK_HHV6Z antibody is a specialized immunological reagent designed to target antigens associated with Human Herpesvirus 6 (HHV-6), a member of the *Roseolovirus* genus. HHV-6 exists as two distinct species, HHV-6A and HHV-6B, both known for their tropism toward CD4+ T cells and association with conditions like roseola infantum, encephalitis, and potential links to chronic diseases such as multiple sclerosis. The "GCVK" designation in the antibody’s name likely refers to a specific viral glycoprotein or epitope critical for viral entry or immune evasion, though its exact molecular target remains to be fully characterized. HHV-6Z, a less commonly referenced variant or strain, may imply unique antigenic features distinguishing it from typical HHV-6A/B isolates.
This antibody is typically developed using recombinant viral proteins or peptide immunogens, often in murine or rabbit host systems, and validated for applications like immunofluorescence, Western blotting, or ELISA. Its utility lies in advancing HHV-6 research, including viral pathogenesis studies, latency/reactivation mechanisms, and diagnostic assay development. Due to HHV-6’s persistence in host tissues and debated role in chronic illnesses, GCVK_HHV6Z also holds potential for therapeutic exploration, such as monoclonal antibody therapies or vaccine design. However, cross-reactivity with other herpesviruses or host proteins remains a key validation challenge. Further studies are needed to clarify its specificity and functional relevance in both research and clinical contexts.
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