| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Homeobox protein Hox-C6; Hox-3C; HHO.C8; CP25; HOXC6 |
| Entrez GeneID | 3223; |
| WB Predicted band size | 26kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from C-terminal of human HOXC6. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于HOXC6抗体的3篇参考文献示例(文献信息为模拟，仅供格式参考)：
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1. **文献名称**：HOXC6 Expression in Prostate Cancer: Correlation with Tumor Aggressiveness
**作者**：Smith A et al.
**摘要**：本研究利用HOXC6特异性抗体，通过免疫组化分析前列腺癌组织中HOXC6的表达水平，发现其高表达与肿瘤的高Gleason评分和转移风险显著相关，提示HOXC6可能作为前列腺癌进展的生物标志物。
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2. **文献名称**：HOXC6 Regulates Hair Follicle Stem Cell Activation via Wnt Signaling
**作者**：Lee J et al.
**摘要**：通过HOXC6抗体的免疫荧光染色，揭示HOXC6在小鼠皮肤毛囊干细胞中的动态表达模式，证实其通过调控Wnt通路基因参与毛囊周期再生，为脱发治疗提供潜在靶点。
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3. **文献名称**：HOXC6 as a Prognostic Marker in Gastric Adenocarcinoma
**作者**：Garcia R et al.
**摘要**：采用HOXC6抗体对胃癌组织进行Western blot和免疫组化分析，发现HOXC6过表达与患者生存期缩短和化疗耐药相关，提示其可作为胃癌预后评估的分子指标。
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注：以上文献信息为示例，实际引用需以真实发表的论文为准。建议通过PubMed或Web of Science以“HOXC6 antibody”及关联关键词检索最新研究。
The HOXC6 antibody is a tool used to detect the HOXC6 protein, a member of the homeobox (HOX) gene family. HOX genes encode transcription factors critical for embryonic development, particularly in establishing body patterning and organogenesis. HOXC6. located on chromosome 12q13.13. regulates cellular differentiation, proliferation, and apoptosis. Dysregulation of HOXC6 has been implicated in various cancers, including prostate, breast, and ovarian cancers, where it may act as an oncogene by promoting tumor growth, metastasis, or therapy resistance.
HOXC6 antibodies are widely employed in research to study its expression and function in normal and pathological tissues. These antibodies enable techniques like immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting, helping to map HOXC6's tissue-specific localization and quantify its levels. Commercially available HOXC6 antibodies vary in host species (e.g., mouse, rabbit), clonality (monoclonal/polyclonal), and epitope specificity, requiring validation for target applications.
Recent studies highlight HOXC6's role in cancer stemness and epithelial-mesenchymal transition (EMT), linking it to poor prognosis. However, its context-dependent roles—acting as either an oncogene or tumor suppressor in different cancers—underscore the complexity of HOX protein biology. HOXC6 antibodies thus serve as essential reagents for unraveling its mechanistic contributions to development and disease, with potential diagnostic or therapeutic implications. Researchers must validate these antibodies rigorously due to cross-reactivity risks and variability in experimental conditions.
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