关键信息
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基因名
Ephrin-B1/EFNB1
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简介
Ephrin-B1/EFNB1 proteins are cell surface ligands of Eph receptors that critically regulate migration, repulsion, and adhesion during neuronal, vascular, and epithelial development. Ephrin-B1/EFNB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Ephrin-B1/EFNB1 protein, expressed by HEK293 , with C-His labeled tag.
- 应用
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别名
Ephrin-B1; EFL-3; ELK-L; LERK-2; Ephrin-B1 CTF; EFNB1; EFL3; EPLG2; LERK2
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P52795
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表达区间
K30-S229
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氨基酸序列
MARPGQRWLSKWLVAMVVLTLCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNKPHQEIRFTIKFQEFSPNYMGLEFKKYHDYYITSTSNGSLEGLENREGGVCRTRTMKIVMKVGQDPNAVTPEQLTTSRPSKESDNTVKTATQAPGRGSQGDSDGKHETVNQEEKSGPGAGGGGSGDS
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蛋白长度
Partial
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分子量
33-38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Ephrin-B1, encoded by the EFNB1 gene, is a member of the ephrin family, which plays a critical role in various biological processes, including neuronal development, angiogenesis, and cell adhesion. Research on Ephrin-B1 has gained momentum due to its involvement in cell signaling pathways mediated by Eph receptors, particularly in the context of developmental biology and cancer. The Ephrin-B1/Eph receptor interaction is crucial for bidirectional signaling, influencing cellular responses and tissue organization. Aberrant expression or mutations in EFNB1 have been linked to several pathological conditions, including tumors and neurological disorders. The study of recombinant Ephrin-B1 proteins allows for detailed exploration of their functional roles and mechanisms. By producing these proteins in a laboratory setting, researchers aim to investigate how Ephrin-B1 mediates cellular communication and promotes various biological responses. This understanding could uncover potential therapeutic targets for diseases where Ephrin-B1 signaling is disrupted, ultimately contributing to advances in treatment strategies for related health issues. The development and characterization of Ephrin-B1 recombinant proteins offer valuable insights into their structure-function relationships, potentially paving the way for novel interventions in regenerative medicine and oncology.
