Rabbit Polyclonal HOXA11 Antibody

The HOXA11 antibody is a crucial tool in studying the HOXA11 protein, a member of the homeobox (HOX) gene family, which plays pivotal roles in embryonic development, particularly in patterning body structures and organogenesis. HOXA11 is specifically implicated in the development of the uterus, limbs, and urogenital system. Dysregulation of HOXA11 expression has been linked to reproductive disorders, such as endometriosis and uterine factor infertility, as well as certain cancers, including ovarian and endometrial carcinomas. In research, the HOXA11 antibody is widely used to detect and quantify HOXA11 protein levels via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These applications help elucidate HOXA11’s spatial and temporal expression patterns during development and disease. Additionally, studies utilizing this antibody have revealed HOXA11’s role in cellular differentiation, tissue remodeling, and its interaction with signaling pathways like Wnt and TGF-β. Recent advances also highlight its potential involvement in epigenetic regulation and cancer metastasis. As a transcription factor, HOXA11 binds DNA to regulate target genes, making its antibody essential for exploring gene regulatory networks. Validated for specificity in human and model organisms, the HOXA11 antibody remains indispensable for developmental biology, oncology, and reproductive health research.