关键信息
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基因名
SDF-1 beta/CXCL12
- 应用
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别名
C-X-C motif chemokine 12; Stromal cell-derived factor 1; CXCL12; SDF-1β
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种属
Rat
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
NP_001029054.1
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表达区间
K22-M93
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蛋白长度
Full Length of Mature Protein
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of SDF-1 beta (stromal cell-derived factor 1 beta), also known as CXCL12, has gained considerable attention due to its critical role in various biological processes, including hematopoiesis, angiogenesis, and the immune response. SDF-1 beta is a chemokine that acts as a chemoattractant for various cell types, particularly in the contexts of stem cell migration and tissue repair. Its interaction with the CXCR4 receptor is pivotal for guiding stem cells to sites of injury and inflammation, making it an essential factor in regenerative medicine. Moreover, dysregulation of the SDF-1/CXCR4 axis has been implicated in several pathological conditions, such as cancer metastasis and autoimmune diseases. Research on recombinant SDF-1 beta protein focuses on elucidating its structure-function relationships, optimizing its therapeutic potential, and exploring its mechanisms of action. By generating and characterizing recombinant SDF-1 beta, scientists aim to develop novel treatment strategies for enhancing stem cell mobilization, improving tissue regeneration, and potentially addressing various diseases linked to its signaling pathways. The ongoing investigation into this chemokine holds promise for advancing our understanding of cell migration and its broader implications in health and disease.
