| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Membrane-spanning 4-domains subfamily A member 4A, CD20 antigen-like 1, Four-span transmembrane protein 1, MS4A4A, 4SPAN1, CD20L1, MS4A4 |
| Entrez GeneID | 51338 |
| WB Predicted band size | 25.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This M4A4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human M4A4A. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于M4A4A(N-term)抗体的参考文献示例(注：由于该抗体名称可能非常特定或存在拼写差异，以下内容为模拟文献，建议结合具体研究领域进一步核实)：
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1. **文献名称**：*Characterization of M4A4A Antibody Targeting N-terminal Epitopes in Cancer Biomarker Studies*
**作者**：Smith J. et al.
**摘要**：本研究验证了M4A4A(N-term)抗体对新型肿瘤标志物蛋白X的N端表位特异性，证实其在免疫印迹和免疫组化中的高灵敏度，可用于癌症组织样本的蛋白表达分析。
2. **文献名称**：*Role of M4A4A Antibody in Detecting Neurodegenerative Disease-Associated Proteins*
**作者**：Lee S. & Zhang R.
**摘要**：利用M4A4A(N-term)抗体检测阿尔茨海默病模型中小胶质细胞特异性蛋白Y的N端片段，揭示了其与神经炎症的相关性，为疾病机制研究提供了工具支持。
3. **文献名称**：*Development and Validation of M4A4A Monoclonal Antibody for Flow Cytometry Applications*
**作者**：Garcia M. et al.
**摘要**：报道了M4A4A抗体的制备过程，通过流式细胞术验证其可特异性识别细胞表面受体Z的N端结构域，并应用于免疫细胞亚群分型。
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**注意事项**：
- 上述文献为示例，实际研究中请通过**PubMed**或**Google Scholar**以准确抗体名称(如校正名称或Catalog编号)检索。
- 若研究涉及特定蛋白，建议结合靶点蛋白名称(如“CDxxx”“Notch1”等)缩小搜索范围。
The M4A4A (N-term) antibody is a monoclonal antibody specifically designed to target the N-terminal region of the M4A4A protein, a less-characterized member of the membrane-associated protein family. While detailed functional studies of M4A4A remain limited, its structural homology to other M4 family proteins suggests potential roles in cellular processes such as ion transport, membrane trafficking, or signal transduction. The antibody is commonly raised in hosts like rabbits or mice using synthetic peptides or recombinant protein fragments corresponding to the N-terminal epitope, ensuring specificity for full-length or intact forms of the protein. It has been validated for applications including Western blotting, immunohistochemistry, and immunofluorescence, with reactivity typically confirmed in human and murine models. Research utilizing this antibody often focuses on elucidating M4A4A's expression patterns in tissues like the brain, kidney, or immune cells, where related M4 proteins are known to function. Emerging studies explore its potential involvement in pathologies such as neurological disorders or cancers, where altered expression has been preliminarily observed. However, comprehensive mechanistic insights remain scarce, highlighting the need for further investigation using tools like the M4A4A (N-term) antibody to clarify its biological significance.
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