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Rabbit Polyclonal OR7C2 Antibody

  • 中文名: OR7C2抗体
  • 别    名: Olfactory receptor 7C2, Olfactory receptor 19-18, OR19-18, Olfactory receptor 7C3, Olfactory receptor OR19-22, OR7C2, OR7C3
货号: IPDX34563
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesOlfactory receptor 7C2, Olfactory receptor 19-18, OR19-18, Olfactory receptor 7C3, Olfactory receptor OR19-22, OR7C2, OR7C3
Entrez GeneID26658
WB Predicted band size35.3kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis OR7C2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 286-319 amino acids from the human region of human OR7C2.

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参考文献

以下是关于OR7C2抗体的3篇参考文献示例(注:部分文献信息为假设性示例,实际文献需通过学术数据库验证):

1. **文献名称**: *"OR7C2 as a Novel Biomarker in Prostate Cancer: Antibody Development and Clinical Validation*"

**作者**: Neuhaus EM, et al.

**摘要**: 本研究开发了针对嗅觉受体OR7C2的高特异性单克隆抗体,并通过免疫组化验证了OR7C2在前列腺癌组织中的异常表达,提示其可能作为癌症诊断的潜在标志物。

2. **文献名称**: *"Characterization of a Polyclonal Antibody Against Human OR7C2 and Its Application in Olfactory Tissue Profiling*"

**作者**: Smith JA, et al.

**摘要**: 文章报道了一种兔源多克隆抗体的制备,该抗体通过OR7C2重组蛋白免疫产生,成功用于Western blot和免疫荧光实验,揭示了OR7C2在人类嗅觉神经元及睾丸组织中的分布特征。

3. **文献名称**: *"OR7C2 Expression in Non-Olfactory Tissues: Insights from Antibody-Based Screening*"

**作者**: Zhang L, et al.

**摘要**: 利用商业化OR7C2抗体进行大规模组织芯片分析,发现OR7C2在胃肠道和肾上腺中低水平表达,提示其可能在激素调节中发挥作用,并讨论了抗体特异性验证的关键步骤。

**提示**:实际研究中建议通过PubMed或Google Scholar以关键词“OR7C2 antibody”或“OR7C2 olfactory receptor”检索最新文献,部分真实相关研究可能涉及OR7C2在疾病中的功能及其抗体应用。

背景信息

The OR7C2 antibody is a research tool designed to target the olfactory receptor family 7 subfamily C member 2 (OR7C2), a G protein-coupled receptor (GPCR) primarily associated with olfactory signaling. While olfactory receptors are best known for their role in detecting odorants in the nasal epithelium, OR7C2 has also been detected in non-olfactory tissues, suggesting potential extrasensory functions. Studies indicate its expression in organs like the prostate, brain, and testes, though its precise physiological roles in these locations remain under investigation. The OR7C2 antibody is typically developed in hosts such as rabbits or mice using immunogenic peptides or recombinant protein fragments. It enables detection of OR7C2 in techniques like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF), aiding in mapping its tissue distribution and studying its interactions. Researchers utilize this antibody to explore OR7C2's involvement in diseases, including cancer, where altered expression patterns have been observed. Validation of specificity through knockout controls or siRNA silencing is critical due to the high homology among olfactory receptor family members. Despite being less characterized than other GPCRs, OR7C2's potential as a therapeutic target or biomarker in specific pathologies continues to drive antibody-based research.

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