Rabbit Polyclonal C9orf100 Antibody

The C9orf100 antibody is a research tool designed to target the protein encoded by the C9orf100 gene (Chromosome 9 Open Reading Frame 100), a poorly characterized gene located on human chromosome 9. While the precise biological function of the C9orf100 protein remains unclear, it is hypothesized to play roles in cellular processes such as proliferation, differentiation, or signaling, based on conserved domains or indirect experimental associations. Antibodies against C9orf100 are primarily used in basic research to investigate its expression patterns, subcellular localization, and interactions in various tissues or cell types. These antibodies are often validated in applications like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF) to map protein distribution under physiological or pathological conditions. Interest in C9orf100 has grown due to genomic studies linking its locus to disease susceptibility regions, though direct evidence of its involvement in specific disorders remains limited. Current research focuses on exploring its potential relevance in cancer, neurodegenerative diseases, or metabolic syndromes using knockout models or overexpression systems. However, the lack of comprehensive functional data and standardized validation protocols for C9orf100 antibodies poses challenges, necessitating careful experimental controls. Commercial C9orf100 antibodies are typically polyclonal or monoclonal reagents raised against peptide antigens derived from predicted epitopes, with validation data varying by supplier. Ongoing studies aim to clarify its molecular interactions and pathways to establish its utility as a biomarker or therapeutic target.